24423-87-8

Upstream product

• 91-21-4 1,2,3,4-tetrahydroisoquinoline 
• 623-00-7 4-bromobenzenecarbonitrile 
• 75-05-8 acetonitrile 
• 22901-09-3 2-(2-bromoethyl)benzaldehyde 

Downstream Products

• 91-21-4 1,2,3,4-tetrahydroisoquinoline 
• 21939-14-0 10-phenyl-(8ar,11ac,11bc)-5,8a,11a,11b-tetrahydro-6H-pyrrolo[3',4':4,5]isoxazolo[3,2-a]isoquinoline-9,11-dione 
• 19332-04-8 2-phenyl-1,5,6,10b-tetrahydro-2H-isoxazolo[3,2-a]isoquinoline 
• 72502-79-5 9,9-dimethyl-12,12-diphenyl-5,9,12,13a-tetrahydro-6H-9λ⁵-[1,2]azaphospholo[2',1':2,3][1,3,5,2]oxadiazaphospholo[4,5-a]isoquinoline-10,11-dicarboxylic acid dimethyl ester 
• 19332-08-2 2,2-diphenyl-1,5,6,10b-tetrahydro-2H-isoxazolo[3,2-a]isoquinoline 
• 20521-06-6 (8at,12at,12bc)-5,8a,9,10,11,12,12a,12b-octahydro-6H-9r,12c-methano-benzo[4,5]thiazolo[3,2-a]isoquinoline-10ξ,11ξ-dicarboxylic acid dimethyl ester 
• 72502-80-8 9,9,12,12-tetraphenyl-5,9,12,13a-tetrahydro-6H-9λ⁵-[1,2]azaphospholo[2',1':2,3][1,3,5,2]oxadiazaphospholo[4,5-a]isoquinoline-10,11-dicarboxylic acid dimethyl ester 
• 21978-66-5 1-phenyl-1,5,6,10b-tetrahydro-[1,2,4]oxadiazolo[3,2-a]isoquinolin-2-one 
• 89768-84-3 2-phenyl-6,10b-dihydro-5H-isoxazolo[3,2-a]isoquinoline-1-carboxylic acid methyl ester 
• 22278-43-9 2-phenyl-5,6-dihydro-2H-isoxazolo[3,2-a]isoquinoline-1-carboxylic acid ethyl ester 
• 3230-65-7 3,4-dihydroisoquinoline 
• 51849-22-0 iodomethyl phenyl sulfide 
• 77877-20-4 (4R,5S)-4-methyl-5-phenyl-3-propionyloxazolidin-2-one 
• 101212-35-5 (2S,4R,5S)-3-(3-phenylthiomethyl-1-oxopropyl)-5-phenyl-oxazolidin-2-one 

Relevant academic research and scientific papers

Metal-Free Solvent Promoted Oxidation of Benzylic Secondary Amines to Nitrones with H2O2

An environmentally benign protocol for the generation of nitrones from benzylic secondary amines via catalyst-free oxidation of secondary amines using H2O2 in MeOH or CH3CN is described. This methodology provides a selective access to a variety of C-aryl nitrones in yields of 60 to 93%. Several studies have been performed to shed light on the reaction mechanism and the role of the solvent.

Molybdenum oxide/bipyridine hybrid material {[MoO3(bipy)] [MoO3(H2O)]}n as catalyst for the oxidation of secondary amines to nitrones

The inorganic-organic hybrid material {[MoO3(bipy)][MoO 3(H2O)]}n (bipy = 2,2′-bipyridine) can be used as a water-tolerant catalyst for the oxidation of secondary amines under mild conditions using either urea hydrogen peroxide (UHP) or tert-butylhydroperoxide (TBHP) as the oxidant. Under optimized reaction conditions (2 mol % catalyst, 3-4 equiv TBHP, CH2Cl2 as the solvent, 40 °C), the corresponding nitrones were obtained with different efficiency depending on the nature of the cyclic or acyclic amine used.