24447-21-0Relevant articles and documents
Palladium-catalysed addition of potassium phenyltrifluoroborate to dinitriles: Synthesis of diketone compounds
Wang, Xingyong,Wang, Qingzong,Chen, Jiuxi,Liu, Miaochang,Ding, Jinchang,Wu, Huayue
, p. 470 - 472 (2013/09/12)
Pd(OAc)2/1,10-phenanthroline-catalysed addition of potassium phenyltrifluoroborate to aliphatic dinitriles in 2-MeTHF has been developed, achieving diphenyl diones in moderate to excellent yields. The scope of the developed approach was successfully explored toward the addition of potassium phenyltrifluoroborate to aromatic dinitriles. Additionally, a plausible pathway for the formation of the diones has been proposed.
Nucleophilic benzoylation using lithiated methyl mandelate as a synthetic equivalent of the benzoyl carbanion. Oxidative decarboxylation of α-hydroxyacids
Blay, Gonzalo,Fernández, Isabel,Formentin, Pilar,Monje, Belén,Pedro, José R,Ruiz, Rafael
, p. 1075 - 1081 (2007/10/03)
The synthesis of alkyl aryl ketones using lithiated methyl mandelate as a synthetic equivalent of the benzoyl carbanion is reported (Umpolung). The methodology involves alkylation of methyl mandelate, hydrolysis of the ester group and oxidative decarboxylation of the resulting α-hydroxyacids. The last step is carried out in a catalytic aerobic way using a Co(III) complex in the presence of pivalaldehyde under very mild and advantageous conditions. The procedure is also applied to methyl mandelates substituted on the aromatic ring.
METHODS FOR SYNTHESIS OF AROMATIC BIS-1,2-DIKETONES, BISMETHOXYSTYRYLS, AND BISDEOXYBENZOINS FROM 1,4-DISTYRYLBENZENE
Filimonov, V. D.,Yusubov, M. S.,Ogorodnikov, V. D.
, p. 753 - 756 (2007/10/02)
trans,trans-1,4-Distyrylbenzene was converted finally into 1,4-di(phenylglyoxaloyl)benzene by methoxybromination of the double bonds with N-bromosuccinimide in methanol, dehydrobromination, hydrolysis, and oxidation of the intermediate products.The methoxybromination is stereoselective but not regioselective.
