24512-97-8

Upstream product

• 637-81-0 ethyl-2-azidoacetate 
• 529-20-4 2-methylphenyl aldehyde 

Downstream Products

• 1007117-19-2 ethyl 4-acetyl-2-(2-methylphenyl)-5-methyl-1H-pyrrole-3-carboxylate 
• 16732-80-2 4-methyl-1H-indole-2-carboxylic acid ethyl ester 
• 81803-51-2 3-o-Tolyl-3H-azirine-2-carboxylic acid ethyl ester 
• 50458-79-2 ethyl isoquinoline-3-carboxylate 

Relevant academic research and scientific papers

Synthesis of polysubstituted N-H pyrroles from vinyl azides and 1,3-dicarbonyl compounds

(Chemical Equation Presented) Two synthetic methods for tetra- and trisubstituted N-H pyrroles are presented: (i) the thermal pyrrole formation by the reaction of vinyl azides with 1,3-dicarbonyl compounds via the 1,2-addition of 1,3-dicarbonyl compounds to 2H-azirine intermediates generated in situ from vinyl azides; (ii) the Cu(II)-catalyzed synthesis of pyrroles from α-ethoxycarbonyl vinyl azides and ethyl acetoacetate through the 1,4-addition reaction of the acetoacetate to the vinyl azides. By applying these two methods, regioisomeric pyrroles can be prepared selectively starting from the same vinyl azides.

Novel triazole derivatives, process for their preparation and pharmaceutical compositions containing them

The invention relates to a compound of formula in which R1, X1, X2, X3, X4, R4, Y1, Y2 and Y3 are as defined in claim 1. These compounds are CCK-receptor agonists.