24555-54-2Relevant academic research and scientific papers
Retro-Ene Reactions in Heterocyclic Synthesis. II. A Facile Synthetic Method for 4-Hydroxy-2-pyridones
Ito, Kunio,Miyajima, Shingo
, p. 1037 - 1044 (2007/10/02)
Schiff's bases 1 derived from ketones and t-butylamine reacted with diphenyl malonate, diphenyl methylmalonate and diphenyl phenylmalonate to give 4-hydroxy-2-pyridones 4-6.Schiff's bases 1 on reaction with trimethyl methanetricarboxylate afforded 4-hydro
Aktive Malonester als Synthons fuer Heterocyclen: Eine Methode zur Hertstellung von 4-Hydroxy-2(1H)-pyridonen
Kappe, Thomas,Ajili, Samir,Stadlbauer, Wolfgang
, p. 463 - 468 (2007/10/02)
4-Hydroxy-2-(1H)-pyridones 3 can be obtained in excellent yields from azomethines 1 with trichlorophenylmalonates 2.The variation of the substituents in position 1,3,5 or 6, respectively is possible over a wide range.In this manner the 5,6-fused-pyridones
