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246506-79-6

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246506-79-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 246506-79-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,6,5,0 and 6 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 246506-79:
(8*2)+(7*4)+(6*6)+(5*5)+(4*0)+(3*6)+(2*7)+(1*9)=146
146 % 10 = 6
So 246506-79-6 is a valid CAS Registry Number.

246506-79-6Relevant articles and documents

Discovery of a novel chimeric ubenimex–gemcitabine with potent oral antitumor activity

Jiang, Yuqi,Hou, Jinning,Li, Xiaoyang,Huang, Yongxue,Wang, Xuejian,Wu, Jingde,Zhang, Jian,Xu, Wenfang,Zhang, Yingjie

, p. 5787 - 5795 (2016)

Herein, a novel mutual prodrug BC-A1 was discovered by integrating ubenimex and gemcitabine into one molecule. Biological characterization revealed that compound BC-A1 could maintain both the anti-CD13 activity of ubenimex and the cytotoxic activity of ge

MULTI-TARGETED UBENIMEX PRODRUG DERIVATIVE AND PREPARATION METHOD AND USE THEREOF

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Paragraph 0065, (2015/12/08)

The present invention relates to the design, synthesis, and biological study of multi-targeted Ubenimex pro-drug derivative. More particularly, provided in the present invention is a compound as shown by general structural formula (I) (wherein the definit

Application of acyl cyanophosphorane methodology to the synthesis of protease inhibitors: Poststatin, eurystatin, phebestin, probestin and bestatin

Wasserman, Harry H.,Petersen, Anders K.,Xia, Mingde

, p. 6771 - 6784 (2007/10/03)

Full details are given for the syntheses of the protease inhibitors, poststatin and eurystatin by the acyl cyanophosphorane coupling procedure used for the formation of α-keto amides. We have also extended this methodology to the syntheses of the related α-hydroxy amide natural products, phebestin, probestin and bestatin. The key step in the latter synthetic sequences involved diastereomeric selectivity in the reduction of the α-keto precursor to the corresponding α-hydroxy amide by the use of zinc borohydride.

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