24665-93-8

Basic information

• Product Name: 4,5-dihydro-1,3-oxazol-2-amine
• Synonyms: 4,5-dihydro-1,3-oxazol-2-amine;4,5-dihydrooxazol-2-amine
• CAS NO: 24665-93-8
• Molecular Formula: C₃H₆N₂O
• Molecular Weight: 86.09254
• Mol File: 24665-93-8.mol
• Article Data: 5

Chemical Properties

• Melting Point: 105 °C
• Boiling Point: 148.5°Cat760mmHg
• Flash Point: 43.6°C
• Appearance: /
• Density: 1.44g/cm³
• Vapor Pressure: 4.21mmHg at 25°C
• Refractive Index: 1.591
• PKA: 8.71±0.50(Predicted)
• CAS DataBase Reference: 4,5-dihydro-1,3-oxazol-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-dihydro-1,3-oxazol-2-amine(24665-93-8)
• EPA Substance Registry System: 4,5-dihydro-1,3-oxazol-2-amine(24665-93-8)

Safety Data

• Hazardous Substances Data: 24665-93-8(Hazardous Substances Data)

Usage

General Description

4,5-dihydro-1,3-oxazol-2-amine, also known as 4,5-dihydro-2-oxazolamine, is an organic compound with the chemical formula C3H6N2O. It is a heterocyclic amine that consists of a five-membered ring containing oxygen and nitrogen atoms. 4,5-dihydro-1,3-oxazol-2-amine is used in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. It has potential applications in medicinal chemistry due to its structural features, as well as its chemical reactivity. 4,5-dihydro-1,3-oxazol-2-amine has also been studied for its potential biological activities and has shown promise in various pharmacological and biochemical studies.

InChI:InChI=1/C3H6N2O/c4-3-5-1-2-6-3/h1-2H2,(H2,4,5)

Upstream product

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Downstream Products

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Relevant articles and documents

Combination Therapy for Tuberculosis

The present invention relates to methods of treating tuberculosis, including multi-drug resistant varieties and latent tuberculosis. More particularly, the present invention relates to a method of treating tuberculosis in a mammal comprising administering to said mammal in need thereof an effective amount of a compound of formula (I), (S)—N-[[3-[3-fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide, or a pharmaceutically acceptable salt thereof in combination with at least two agents useful in the treatment of tuberculosis. The present invention also relates to a pharmaceutical composition comprising a therapeutically effective amount of a compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof, (ii) a therapeutically effective amount of at least one agent useful in the treatment of tuberculosis and (iii) one or more pharmaceutically acceptable carriers or vehicles.

Compounds useful as anti-inflammatory agents

Disclosed are novel aromatic compounds of the formula(I) wherein G, E, W, Ar, X, Y and Z. The compounds are useful for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are pharmaceutical compositions containing and processes of making such compounds.

2-Amino-2-oxazolines and process for preparing them

New 2-amino-2-oxazolines and their salts with physiologically tolerated acids which may be used as medicaments, in particular as antihypotonics, diuretics or antiphlogistics, and process for preparing them.