4353-52-0

Usage

Uses

Used in Pharmaceutical Synthesis:
1-(2-HYDROXYETHYL)GUANIDINE is used as an intermediate in the synthesis of various pharmaceuticals for its versatile chemical structure and potential therapeutic applications.
Used in Antimicrobial Applications:
1-(2-HYDROXYETHYL)GUANIDINE is used as an antimicrobial agent for its potential to combat bacteria and fungi, making it a valuable compound in the development of new treatments for infectious diseases.
Used in Corrosion Inhibition:
In the Oil and Gas Industry, 1-(2-HYDROXYETHYL)GUANIDINE is used as a corrosion inhibitor to protect metal surfaces from degradation, thereby enhancing the longevity and efficiency of industrial equipment and infrastructure.
Used in Research and Development:
1-(2-HYDROXYETHYL)GUANIDINE is utilized as a compound in research and development for its potential applications in various scientific fields, including material science, pharmaceuticals, and biotechnology.

InChI:InChI=1/C3H9N3O/c4-3(5)6-1-2-7/h7H,1-2H2,(H4,4,5,6)

Upstream product

• 24665-93-8 2-Imino-1,3-oxazolidin 
• 867-44-7 S-Methylisothiourea sulfate 
• 141-43-5 ethanolamine 
• 24665-93-8 4,5-dihydro-oxazol-2-ylamine 
• 64-17-5 ethanol 
• 420-04-2 CYANAMID 
• 4023-02-3 1H-pyrazole-1-carboximidamide hydrochloride 
• 476667-20-6 C₁₉H₂₁N₃O₅ 
• 2986-20-1 S-ethylisothiourea 

Downstream Products

• 46885-84-1 N-[2-(2,6-Dichloro-phenyl)-acetyl]-N'-(2-hydroxy-ethyl)-guanidine 
• 68656-85-9 1-[1-Amino-1-(2-hydroxy-ethylamino)-meth-(Z)-ylidene]-3-(2,6-dimethyl-phenyl)-urea 
• 24665-93-8 4,5-dihydro-oxazol-2-ylamine 

Relevant academic research and scientific papers

In Vitro and in Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas

A newly validated target for tuberculosis treatment is phosphopantetheinyl transferase, an essential enzyme that plays a critical role in the biosynthesis of cellular lipids and virulence factors in Mycobacterium tuberculosis. The structure-activity relat

Discovery of 5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine inhibitors of Erk2

The discovery and optimization of a series of tetrahydropyridopyrimidine based extracellular signal-regulated kinase (Erks) inhibitors discovered via HTS and structure based drug design is reported. The compounds demonstrate potent and selective inhibition of Erk2 and knockdown of phospho-RSK levels in HepG2 cells and tumor xenografts.

Discovery of 5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine inhibitors of Erk2

The discovery and optimization of a series of tetrahydropyridopyrimidine based extracellular signal-regulated kinase (Erks) inhibitors discovered via HTS and structure based drug design is reported. The compounds demonstrate potent and selective inhibition of Erk2 and knockdown of phospho-RSK levels in HepG2 cells and tumor xenografts.

PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS

The invention relates to a process for straightening keratin fibres, comprising: (i) a step in which a straightening composition containing at least two denaturing agents is applied to the keratin fibres, (ii) a step in which the temperature of the keratin fibres is raised, using a heating means, to a temperature of between 110 and 250° C.

Amidination of amines under microwave conditions using recyclable polymer-bound 1H-pyrazole-1-carboxamidine

A convenient one-step transformation of primary and secondary amines into the corresponding unprotected guanidines using 4-benzyl-3,5-dimethyl-1H- pyrazole-1-carboxamidine and its polymer-bound variant is described. The scopes and limitations of the method, the microwave-assistance of amidination as well as a recycling protocol are examined. Georg Thieme Verlag Stuttgart.

A new reagent and its polymer-supported variant for the amidination of amines

New reagents for the high yielding amidination of primary and secondary amines are described. By attaching a benzyl substituent to the 3,5-dimethyl-1H-pyrazole-1-carboxamidine ring, a reagent 1 is obtained which allows easy work-up after amidination because of solubility of byproducts in organic solvents. In addition, the polystyrene-bound analogue 2 was prepared which allows amidination of various amines with high purity.