247127-63-5

Basic information

• Product Name: 2-Hydroxy-4-[2-(pyrimidine-2ylamino)ethoxy]benzoic acid
• Synonyms: 2-Hydroxy-4-[2-(pyrimidine-2ylamino)ethoxy]benzoic acid
• CAS NO: 247127-63-5
• Molecular Weight: 275.264
• Mol File: 247127-63-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Hydroxy-4-[2-(pyrimidine-2ylamino)ethoxy]benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Hydroxy-4-[2-(pyrimidine-2ylamino)ethoxy]benzoic acid(247127-63-5)
• EPA Substance Registry System: 2-Hydroxy-4-[2-(pyrimidine-2ylamino)ethoxy]benzoic acid(247127-63-5)

Safety Data

• Hazardous Substances Data: 247127-63-5(Hazardous Substances Data)

Upstream product

• 4595-60-2 2-bromopyrimidine 
• 300576-61-8 4-(2-amino-ethoxy)-2-hydroxy-benzoic acid 
• 75-77-4 chloro-trimethyl-silane 
• 247127-62-4 4-(2-Aminoethoxy)-2-hydroxybenzoic acid, hydrochloride 
• 13966-57-9 chlorosilane 
• 247127-73-7 4-(2-tert-butoxycarbonylamino-ethoxy)-2-hydroxy-benzoic acid 
• 247127-60-2 methyl 4-(2-tert-butoxycarbonylamino-ethoxy)-2-hydroxy-benzoate 
• 2150-47-2 methyl 2,4-dihydroxybenzoate 

Downstream Products

• 247127-64-6 2-hydroxy-4-[2-(3,4,5,6-tetrahydropyrimidin-2-ylamino)ethoxy]-benzoic acid 

Relevant articles and documents

Methods for solid phase combinatorial synthesis of integrin inhibitors

Compounds of the formula are useful in the treatment of various disorders including, but not limited to, cancer (tumor metathesis, tumorgenesis/tumor growth), angiogenesis (as in cancer, diabetic retinopathy, rheumatoid arthritis), restenosis (following b

Parallel solid-phase synthesis of vitronectin receptor (αvβ3) inhibitors

A combinatorial approach for rapid optimization of a vitronectin receptor (αvβ3) inhibitor lead was accomplished by solid-phase synthesis. Orthogonally bis protected 2,3-diaminopropionic acid was used to immobilize the C-terminus of the molecule. Selective deprotection and functionalization of the α-amino group followed by acyl resorcinol scaffold attachment and N-terminus diversification was used to explore structure-activity relationship (SAR). (C) 2000 Elsevier Science Ltd. All rights reserved.