247586-21-6Relevant articles and documents
On the enantiomers of 2-dimethylamino-3-pentanone, key intermediates in the synthesis of analgesic alkylaminoalkylnaphthalenes
Collina, Simona,Benevelli, Francesca,Vercesi, Dina,Ghislandi, Victor
, p. 2387 - 2397 (2007/10/03)
2-Dimethylamino-3-pentanone 1 is the key intermediate in the synthesis of alkylaminoalkylnaphthalenic analgesics. In this paper the resolution of this compound with L- and D-dibenzoyltartaric acids is described The behavior of the diastereomeric dibenzoyltartrates and of the enantiomers in solution is investigated by NMR spectroscopy, polarimetry and chiral gas- chromatographic analysis.