24760-47-2Relevant articles and documents
Ru(II)-based complexes with N-(acyl)-N′,N′-(disubstituted)thiourea ligands: Synthesis, characterization, BSA- and DNA-binding studies of new cytotoxic agents against lung and prostate tumour cells
Correa, Rodrigo S.,De Oliveira, Katia M.,Delolo, Fábio G.,Alvarez, Anislay,Mocelo, Raúl,Plutin, Ana M.,Cominetti, Marcia R.,Castellano, Eduardo E.,Batista, Alzir A.
, p. 63 - 71 (2015)
Abstract Four ruthenium(II)-based complexes with N-(acyl)-N′,N′-(disubstituted)thiourea derivatives (Th) were obtained. The compounds, with the general formula trans-[Ru(PPh3)2(Th)(bipy)]PF6, interact with bovine serum alb
Supramolecular self-assembly of new thiourea derivatives directed by intermolecular hydrogen bonds and weak interactions: crystal structures and Hirshfeld surface analysis
Gumus, Ilkay,Solmaz, Ummuhan,Binzet, Gun,Keskin, Ebru,Arslan, Birdal,Arslan, Hakan
, p. 169 - 198 (2018/09/25)
Abstract: We synthesized and characterized a series of four closely related thiourea derivatives (1–4) obtained by reaction of 4-R-benzoyl chloride (R: H, Cl, CH3, and OCH3) with equimolar amount of potassium thiocyanate and dibenzyl
On the cytotoxic activity of Pd(II) complexes of N,N-disubstituted- N′-acyl thioureas
Plutín, Ana M.,Mocelo, Raúl,Alvarez, Anislay,Ramos, Raúl,Castellano, Eduardo E.,Cominetti, Marcia R.,Graminha, Angelica E.,Ferreira, Antonio G.,Batista, Alzir A.
, p. 76 - 82 (2014/03/21)
The rational design of anticancer drugs is one of the most promising strategies for increasing their cytotoxicity and for minimizing their toxicity. Manipulation of the structure of ligands or of complexes represents a strategy for which is possible to mo
Efficient one-pot synthesis of alkyl 2-(dialkylamino)-4-phenylthiazole-5- carboxylates and single-crystal x-ray structure of methyl 2-(diisopropylamino)- 4-phenylthiazole-5-carboxylate
Souldozi, Ali,Ramazani, Ali,Dadrass, Ali Reza,Slepokura, Katarzyna,Lis, Tadeusz
experimental part, p. 339 - 348 (2012/04/10)
The reaction between secondary amines, benzoyl isothiocyanate, and dialkyl acetylenedicarboxylates (=dialkyl but-2-ynedioates) in the presence of silica gel (SiO2) led to alkyl 2-(dialkylamino)-4-phenylthiazole-5- carboxylates in fairly high yi
Synthesis and structural characterization of cobalt(II) and copper(II) complexes with N,N-disubstituted-N′-acylthioureas
O'Reilly, Beatriz,Plutin, Ana M.,Perez, Hiram,Calderon, Osmar,Ramos, Raul,Martinez, Roberto,Toscano, Ruben A.,Duque, Julio,Rodriguez-Solla, Humberto,Martinez-Alvarez, Roberto,Suarez, Margarita,Martin, Nazario
experimental part, p. 133 - 140 (2012/05/20)
A new complexes of Co(II) and Cu(II) with N,N-disubstituted-N′- acylthioureas have been prepared and characterized by elemental analysis, and spectroscopic techniques. The structure of N,N-diethyl-N′-furoylthiourea and Co(II) complexes with N,N-diethyl-N′
Tris-chelate complexes of cobalt(III) with N-[di(alkyl/aryl)carbamothioyl] benzamide derivatives: Synthesis, crystallography and catalytic activity in TBHP oxidation of alcohols
Gunasekaran,Jerome,Ng, Seik Weng,Tiekink, Edward R.T.,Karvembu
body text, p. 156 - 162 (2012/02/16)
New six coordinated tris-chelate cobalt(III) complexes of the type [Co(L)3] (1-4) {where HL = N-[di(alkyl/aryl)carbamothioyl]benzamide derivatives}were prepared from the reaction between CoCl2· 6H2O and N-[di(alkyl/aryl)carbamothioyl]benzamide in ethanol and characterized by elemental analysis and spectral data (UV/Vis, IR, 1H & 13C NMR). The molecular structure of a representative complex [Co(L1)3] (1) [where HL1 = N-(diisopropylcarbamothioyl)benzamide], was determined by single crystal X-ray diffraction method and reveals a distorted octahedral geometry and a facial configuration of S atoms around the Co(III) center. These complexes act as efficient catalysts for the oxidation of alcohols to their corresponding aldehydes or ketones in presence of tert-butyl hydroperoxide (TBHP) at 80°C.
Synthesis, characterization, and catalytic applications of Ru(III) complexes containing N-[di(alkyl/aryl)carbamothioyl]benzamide derivatives and triphenylphosphine/triphenylarsine
Gunasekaran,Karvembu
body text, p. 952 - 955 (2011/01/07)
Six coordinated ruthenium(III) complexes of the type [RuX2(L)(PPh3)2] or [RuX2(L)(AsPh3)2] {where L = N-[di(alkyl/aryl)carbamothioyl]benzamide derivatives, X = Cl or Br} have been prepared by the reaction between [RuX3(PPh3)3] or [RuX3(AsPh3)3] (where X = Cl or Br) and N-[di(alkyl/aryl)carbamothioyl]benzamide derivatives in toluene and characterized by elemental analysis, spectral data (electronic, IR and EPR) and magnetic moment studies. The complexes act as efficient catalysts for the oxidation of alcohols in presence of N-methylmorpholine-N-oxide as oxidant at room temperature.
Antimicrobial activity and structural study of disubstituted Thiourea Derivatives
Cunha, Silvio,MacEdo Jr., Fernando C.,Costa, Giselle A. N.,Rodrigues Jr., Manoel T.,Verde, Rosival B. V.,De Souza Neta, Lourdes C.,Vencato, Ivo,Lariucci, Carlito,Sa, Fernando P.
, p. 511 - 516 (2008/02/03)
The antimicrobial activity of six N-phenyl- and fourteen N-benzoylthiourea derivatives were evaluated from their Minimal Inhibitory Concentration (MIC) values using the microdilution procedure against ten microorganisms. Most of the compounds exhibited selective activity against fungi and Gram-positive bacteria, which were very effectively inhibited by some of the tested thioureas. Additionally, SAR considerations and four novel X-ray diffraction structures of N-benzoylthioureas are included. Springer-Verlag 2007.
Synthesis of 1-benzoyl-3-alkylthioureas by transamidation under microwave in dry media
Márquez, Heiddy,Pérez, Eduardo R.,Plutín, Ana M.,Morales, Margarita,Loupy, André
, p. 1753 - 1756 (2007/10/03)
1-Benzoyl-3,3-diethylthiourea was transamidated with several amines to the corresponding 1-benzoyl-3-alkylthioureas in open vessels under microwave irradiation using a domestic oven. The syntheses were performed in solvent- free conditions on potassium fluoride impregnated alumina. Yields were dramatically improved in comparison with classical heating under the same conditions. (C) 2000 Published by Elsevier Science Ltd.
SYNTHESIS AND STUDY OF NEW N-BENZOYLTHIOUREA DERIVATIVES
Mukmeneva, N. A.,Khabikher, V. Kh.,Cherkasova, O. A.,Cherezova, E. N.,Tuzova, N. G.
, p. 925 - 927 (2007/10/02)
A series of new derivatives of N-benzoylthiourea were synthesized and characterized, and the kinetics of their reactions with cumene hydroperoxide was studied.
