24894-78-8

Usage

Uses

Used in Organic Synthesis:
1-Naphthalenol,6-methyl-(9CI) is used as a synthetic intermediate for the production of various organic compounds. Its unique chemical structure allows it to be a key component in the synthesis of a range of chemical products, contributing to the versatility and functionality of the final products.
Used in Fragrance and Flavor Industry:
In the fragrance and flavor industry, 1-Naphthalenol,6-methyl-(9CI) is utilized for its distinctive aromatic properties. It serves as a valuable ingredient in creating complex and appealing scents and tastes, enhancing the sensory experience of consumer products.
Used in Research and Development:
1-Naphthalenol,6-methyl-(9CI) also finds application in research and development settings, where its chemical properties are studied and explored for potential new uses and applications. This includes investigations into its reactivity, stability, and interactions with other compounds, which can lead to innovative discoveries and advancements in various fields.

Upstream product

• 54714-43-1 2-bromo-6-methyltetralone 
• 91-66-7 N,N-diethylaniline 
• 19061-31-5 1,4-dihydro-1,4-epoxy-6-methylnaphthalene 
• 88-14-2 2-furanoic acid 
• 90500-13-3 5-methyl-2-iodosylbenzoic acid 
• 72839-13-5 1-(2,6-dimethylphenyl)-2-propyn-1-one 
• 91270-68-7 6-bromo-α-naphthol 
• 544-97-8 dimethyl zinc(II) 
• 66361-67-9 6-bromo-3,4-dihydro-2H-naphthalen-1-one 
• 3470-53-9 6-amino-1-tetralone 
• 24894-75-5 1-Methoxy-6-methyl-naphthalin-3-carbonsaeure-methylester 
• 24894-76-6 1-Methoxy-6-methyl-naphthalin-3-carbonsaeure 
• 52548-14-8 2-iodoyl-5-methylbenzoic acid 
• 2305-36-4 4-methylanthranilic acid 

Relevant academic research and scientific papers

ARYNIC SPECIES II; TOSYL AND TRIAZENE AS LEAVING GROUP IN THE GENERATION OF ARYNES FROM POLYMER-BOUND REAGENTS

o-Benzyne and its 4-methyl, 4-chloro and 4-bromo-derivatives were generated in the thermal decomposition of two new kinds of polymer-bound precursors: 1(2-carboxyaryl)triazenes and 2-carboxyaryl-sulphonates.New kinds of trapping polymers for these elusive

COMPOUNDS AND METHODS FOR TREATING HIV INFECTIONS

The present invention is directed to novel nanomolar and picomolar inhibitors of HIV reverse transcriptase, pharmaceutical compositions therefrom and methods for inhibiting reverse transcriptase and treating HIV infections, especially included drug resistant strains of HIV-1 and HIV-2 and/or secondary disease states and/or conditions which occur as a consequence of HIV infection.

Picomolar inhibitors of HIV-1 reverse transcriptase: Design and crystallography of naphthyl phenyl ethers

Catechol diethers that incorporate a 6-cyano-1-naphthyl substituent have been explored as non-nucleoside inhibitors of HIV-1 reverse transcriptase (NNRTIs). Promising compounds are reported that show midpicomolar activity against the wild-type virus and sub-20 nM activity against viral variants bearing Tyr181Cys and Lys103Asn mutations in HIV-RT. An X-ray crystal structure at 2.49 ? resolution is also reported for the key compound 6e with HIV-RT.

Negishi-type coupling of bromoarenes with dimethylzinc

Treatment of bromoarenes with dimethylzinc in the presence of a palladium catalyst provides a high-yielding route to methylarenes. The process accommodates a wide range of aromatic substituents and, in the majority of cases, is free of side reactions.

The Gas-Flow Thermolysis of 1-Isobutenyl Alkynyl and 2-Methylphenyl Alkynyl Ketones. Synthesis of Methylenomycin B

The gas-flow thermolysis of 1-isobutenyl alkynyl or 2-methyphenyl alkynyl ketones were found to lead to phenols and cyclopentenones or to naphthols and indanones, respectively.These conversions involve two cyclization processes so far unknown with α-alkynones; they are interpreted as intramolecular additions of an allylic or a benzylic C,H bond to a triple bond which may occur in two directions.In addition, the cyclopentenones formed by the α-alkynone cyclization, a known carbene process yielding 5-rings, were also found.The available evidence ruled out a carbene process yielding 6-rings.The addition process yielding 5-rings was applied to a short (but low yield) synthesis of methylenomycin B.

ARYNIC SPECIES; EFFECT OF SUBSTITUENTS ON THE REACTIVITY OF MONOSUBSTITUTED DEHYDROBENZENES

Evidence is presented demonstrating the existence of free dehydrobenzenes in the thermal decomposition of diaryliodonium-2-carboxylates, and that o-benzyne itself and its 4-methyl-, 4-chloro-, 4-bromo- and 4-nitro-derivatives are generated from insoluble polymer-bound precursors and trapped by a second solid phase in Diels-Alder reactions.Lifetimes for these elusive species are determined.

GENERATION OF MONOSUBSTITUTED o-BENZYNES FROM POLYMERIC REAGENTS VIA HETEROLYTIC FRAGMENTATIONS

Generation of four 4-substituted o-benzynes by heterolytic fragmentation reactions is demonstrated.