3470-53-9

Basic information

• Product Name: 6-Amino-3,4-dihydro-1(2H)-naphthalenone
• Synonyms: 6-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-ONE;6-AMINO-1,2,3,4-TETRAHYDRO NAPTHALENE-1-ONE;6-AMINO-3,4-DIHYDRO-2H-NAPHTHALEN-1-ONE;6-AMINO-3,4-DIHYDRONAPHTHALEN-1(2H)-ONE;6-Amino-3,4-dihydro-1(2H)-naphthalenone;6-AMINO-1,2,3,4-TETRAHYDRONAPHTHALENE-1-ONE;6-Amino-1-tetralone;6-Amino-3,4-dihydronaphthalene-1(2H)-one
• CAS NO: 3470-53-9
• Molecular Formula: C₁₀H₁₁NO
• Molecular Weight: 161.2
• Product Categories: Amines;Fused Ring Systems
• Mol File: 3470-53-9.mol
• Article Data: 15

Chemical Properties

• Melting Point: 130 °C
• Boiling Point: 359.36 °C at 760 mmHg
• Flash Point: 171.135 °C
• Appearance: /
• Density: 1.193 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.62
• Storage Temp.: 2-8°C
• Solubility: soluble in Methanol
• PKA: 2.20±0.20(Predicted)
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: 6-Amino-3,4-dihydro-1(2H)-naphthalenone(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Amino-3,4-dihydro-1(2H)-naphthalenone(3470-53-9)
• EPA Substance Registry System: 6-Amino-3,4-dihydro-1(2H)-naphthalenone(3470-53-9)

Safety Data

• Hazard Codes: T;Xn,Xi,Xn,T
• Statements: 20/21/22-25
• Safety Statements: 22-26-36/37/39-45
• RIDADR: UN 2811
• WGK Germany: 3
• HazardClass: 6.1
• Hazardous Substances Data: 3470-53-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H11NO/c11-8-4-5-9-7(6-8)2-1-3-10(9)12/h4-6H,1-3,11H2

Upstream product

• 88611-67-0 6-acetamido-1,2,3,4-tetrahydronaphthalen-1-one 
• 7462-74-0 2-bromo-2-methylpropanamide 
• 3470-50-6 6-Hydroxy-1-tetralone 
• 22246-26-0 6-nitrotetralone 
• 1116358-98-5 tert-butyl (5-oxo-5,6,7,8-tetrahydronaphthalen-2-yl)carbamate 
• 1078-19-9 6-methoxy-3,4-dihydro-1(2H)-naphthalenone 
• 418761-91-8 2-methyl-2-[(5-oxo-5,6,7,8-tetrahydro-2-naphthalenyl)oxy]propanamide 
• 418761-92-9 2-hydroxy-2-methyl-N-(5-oxo-5,6,7,8-tetrahydro-2-naphthalenyl)propanamide 
• 50878-03-0 N-(5,6,7,8-tetrahydronaphth-2-yl)acetamide 

Downstream Products

• 90401-84-6 6-cyano-1-tetralone 
• 92651-65-5 6-piperidino-3,4-dihydro-1(2H)-naphthalenone 
• 66361-67-9 6-bromo-3,4-dihydro-2H-naphthalen-1-one 
• 22246-26-0 6-nitrotetralone 
• 852409-48-4 1-(2',4'-dichlorophenyl)-7-iodo-4,5-dihydro-1H-benzo[g]indazole-3-carboxylic acid 
• 852409-44-0 ethyl 1-(2',4'-dichlorophenyl)-7-iodo-4,5-dihydro-1H-benzo[g]indazole-3-carboxylate 
• 125564-40-1 1-tetralone-6-acetic acid 
• 3470-46-0 5-oxo-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid 
• 90401-85-7 ethyl 5-oxo-5,6,7,8-tetrahydronaphthalene-2-carboxylate 
• 90400-90-1 6-Phenyl-3,4-dihydro-2H-naphthalen-1-one oxime 
• 90401-81-3 N-methyl-N-(1-oxo-1,2,3,4-tetrahydro-6-naphthyl)benzamide 
• 76043-07-7 6-Bromo-2-[1-(1-phenylsulfanyl-cyclopropyl)-meth-(E)-ylidene]-3,4-dihydro-2H-naphthalen-1-one 
• 76043-03-3 6-Bromo-2-[hydroxy-(1-phenylsulfanyl-cyclopropyl)-methyl]-3,4-dihydro-2H-naphthalen-1-one 
• 76042-21-2 2-<(1-((2,6-dimethoxyphenyl)thio)cyclopropyl)hydroxymethyl>-6-bromo-3,4-dihydronaphthalen-1(2H)-one 

Relevant articles and documents

Quinoxaline compound, preparation method and application of quinoxaline compound in medicine

The invention provides a quinoxaline compound, a preparation method and application of the quinoxaline compound in medicine, and particularly relates to a quinoxaline compound with PAR4 antagonistic activity, a preparation method of the quinoxaline compound, a pharmaceutical composition containing the quinoxaline compound and application of the quinoxaline compound. Specifically, the invention provides a compound shown as a general formula I and/or II or a tautomer or pharmaceutically acceptable salt thereof, a preparation method of the compound, and application of the compound or the tautomer or the pharmaceutically acceptable salt in medicines for preventing and/or treating thromboembolic diseases.

Keto-benzo[h]-Coumarin-Based Near-Infrared Dyes with Large Stokes Shifts for Bioimaging Applications

Fluorescence imaging is a promising tool for the visualization of biomolecules in living systems and there is great demand for new fluorescent dyes that absorb and emit in the near-infrared (NIR) region. Herein, we constructed three new fluorescent dyes (NBC dyes) based on keto-benzo[h]coumarin (k-BC) and benzopyrilium salts. These dyes showed large Stokes shifts (>100nm) and NIR emission (>800nm). The relationship between the structures and optical properties of these dyes was further investigated by using density functional theory calculations at the B3LYP/6-3G level of theory. Fluorescence images indicated that the fabricated dyes exhibited good photostability and low cytotoxicity and, thus, have potential applications as imaging agents in living cells and animals.

Nitrogen-doped graphene-activated iron-oxide-based nanocatalysts for selective transfer hydrogenation of nitroarenes

Nanoscaled iron oxides on carbon were modified with nitrogen-doped graphene (NGr) and found to be excellent catalysts for the chemoselective transfer hydrogenation of nitroarenes to anilines. Under standard reaction conditions, a variety of functionalized and structurally diverse anilines, which serve as key building blocks and central intermediates for fine and bulk chemicals, were synthesized in good to excellent yields.