2492-30-0

Basic information

• Product Name: ACETOPHENONESEMICARBAZONE
• Synonyms: ACETOPHENONESEMICARBAZONE;1-[(α-Methylbenzylidene)amino]urea;2-(1-Phenylethylidene)-1-hydrazinecarboxamide ,98%
• CAS NO: 2492-30-0
• Molecular Formula: C₉H₁₁N₃O
• Molecular Weight: 177.20314
• Mol File: 2492-30-0.mol
• Article Data: 14

Chemical Properties

• Melting Point: 207～209℃
• Appearance: /
• Density: 1.16 g/cm³
• Refractive Index: 1.576
• PKA: 11.73±0.46(Predicted)
• CAS DataBase Reference: ACETOPHENONESEMICARBAZONE(CAS DataBase Reference)
• NIST Chemistry Reference: ACETOPHENONESEMICARBAZONE(2492-30-0)
• EPA Substance Registry System: ACETOPHENONESEMICARBAZONE(2492-30-0)

Safety Data

• Statements: 36/37/38
• Safety Statements: 36/37/39
• Hazardous Substances Data: 2492-30-0(Hazardous Substances Data)

Usage

Chemical Properties

White solid

InChI:InChI=1/C9H11N3O/c1-7(11-12-9(10)13)8-5-3-2-4-6-8/h2-6H,1H3,(H3,10,12,13)/b11-7+

Upstream product

• 64-17-5 ethanol 
• 1749-19-5 phenyl(1-phenylethylidene)amine 
• 563-41-7 semicarbazide hydrochloride 
• 127-08-2 potassium acetate 
• 4747-13-1 α-methoxystyrene 
• 115525-17-2 (1-phenyl-vinyl)-propyl ether 
• 4426-72-6 hydrazine carboxamide 
• 729-43-1 acetophenonazine 
• 127-09-3 sodium acetate 
• 93-91-4 1-phenylbutan-1,3-dione 
• 495-45-4 dypnone 
• 4316-35-2 acetophenone dimethyl acetal 
• 1139-43-1 1,1,-dipropoxy-1-phenylethane 
• 2302-93-4 acetophenonethiosemicarbazone 

Downstream Products

• 861296-40-4 1-phenyl-5-(1-phenyl-ethylidene)-carbonohydrazide 
• 15940-69-9 acetophenone-(4-o-tolyl semicarbazone) 
• 25445-77-6 4-phenyl-1,2,3-thiadiazole 
• 657-35-2 1,1-difluoroethylbenzene 
• 98-86-2 acetophenone 
• 3141-41-1 1,1-dichloroethylbenzene 
• 19676-38-1 1,1,2-trichloro-1-phenylethane 
• 19676-39-2 (1,1,2,2-tetrachloro-ethyl)-benzene 
• 638-38-0 manganese(II) acetate 
• 93294-52-1 (C₄H₉)3Sn(C₉H₁₀N₃O) 
• 93294-50-9 (C₄H₉)2Sn(C₉H₁₀N₃O)2 
• 1186197-25-0 C₂₁H₂₀N₃OP 
• 26033-20-5 3-Phenyl-1H-pyrazole-4-carboxaldehyde 

Relevant articles and documents

Synthesis and evaluation of antimicrobial and anticancer activities of 3-phenyl-1-phenylsulfonyl pyrazoles containing an aminoguanidine moiety

A series of 3-phenyl-1-phenylsulfonyl pyrazoles containing an aminoguanidine moiety was designed, synthesized, and evaluated for their antimicrobial and anticancer activities. The majority of the target compounds showed broad-spectrum antimicrobial activi

Aminopyrimidine compound, composition containing same and application thereof

The invention discloses an aminopyrimidine compound as shown in a formula (I), preparation and application thereof, and particularly discloses an aminopyrimidine compound as shown in the formula (I),or polymorphism, pharmaceutically acceptable salt, prodr

New approach towards the synthesis of selenosemicarbazones, useful compounds for Chagas' disease

Herein, we describe a new approach towards the synthesis of selenosemicarbazones. The reaction involves an O-Se exchange of semicarbazones using Ishihara reagent. Eleven selenosemicarbazones were prepared using this methodology, with low to moderate yields. Among the prepared compounds the m-bromo phenyl methyl derivative 1b was selected to be evaluated in vivo, in a murine model of acute Chagas' disease. Compound 1b 10 mg/kg bw/day reduced 50% of parasitaemia profile compared with the control group, but was less effective than Benznidazole (50 mg/kg bw/day reduced 90%) and toxic. These studies are important to guide future Chagas drug design.