249291-79-0

Usage

Uses

Used in Pharmaceutical Synthesis:
6-Chloro-3-iodo-2-methylpyridine serves as an intermediate in the synthesis of various pharmaceuticals. Its specific structural features allow it to be a key component in the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Production:
In the agrochemical industry, 6-chloro-3-iodo-2-methylpyridine is utilized as an intermediate for the production of agrochemicals. Its role in this sector is crucial for the creation of effective compounds used in agriculture to protect crops and enhance yields.
Used in Organic Synthesis:
6-Chloro-3-iodo-2-methylpyridine is employed as a building block in organic synthesis for constructing more complex molecules. Its unique combination of functional groups facilitates the formation of a wide range of organic compounds, expanding the scope of chemical research and development.
Used as a Reagent in Chemical Reactions:
Due to its properties and reactivity, 6-chloro-3-iodo-2-methylpyridine is used as a reagent in various chemical reactions. It plays a significant role in the field of synthetic chemistry, enabling the synthesis of novel compounds with potential applications in different industries.

InChI:InChI=1/C6H5ClIN/c1-4-5(8)2-3-6(7)9-4/h2-3H,1H3

Upstream product

• 1824-81-3 2-Amino-6-methylpyridine 
• 132606-40-7 3-bromo-6-chloro-2-methyl-pyridine 
• 1575836-78-0 2-bromomethyl-6-chloro-3-iodopyridine 
• 75073-11-9 5-iodo-6-methyl-pyridin-2-ylamine 

Downstream Products

• 1575831-00-3 1-(2'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-7'H-spiro[azetidine-3,5'-furo[3,4-b]pyridine]-1-yl)-2-(methylsulfonyl)ethanone 
• 1575836-90-6 tert-butyl 2'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-7'H-spiro[azetidine-3,5'-furo[3,4-b]pyridine]-1-carboxylate 
• 1575836-93-9 2'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-7'H-spiro[azetidine-3,5'-furo[3,4-b]pyridine] trifluoroacetate 

Relevant academic research and scientific papers

Synthesis of conformationally constrained spirodihydrofuropyridine analogues of epibatidine

Conformationally constrained spirofuropyridine analogues of epibatidine, syn-2 and anti-2, in which the 7-azabicyclo[2.2.1]heptane system and the 2-chloropyridine ring are held rigidly with the shorter and longer N-N distances, respectively, were synthesized from N-Boc-7-azabicyclo[2.2.1]heptan-2-one. The preliminary binding studies suggested that syn-2 has stronger binding affinity for nAChRs than anti-2.

Synthesis and Reactivity of Triazaphenanthrenes

Pyridonaphthyridines (triazaphenanthrenes) were prepared in 4 steps and in 13-52% overall yield using Negishi cross-couplings between iodopicolines and 2-chloro-pyridylzinc derivatives. After chlorination, Gabriel amination and spontaneous ring-closure, the final aromatization leading to the triazaphenanthrenes was achieved with chloranil. This heterocyclic scaffold underwent a nucleophilic addition at position 6 leading to further functionalized pyridonaphthyridines. The influence of these chemical modifications on the optical properties was studied by steady-state and time-resolved optical spectroscopy. While the thiophene-substituted heterocycles exhibited the most extended absorption, the phenyl- and furan-substituted compounds showed a stronger photoluminescence, reaching above 20% quantum yield and lifetimes of several nanoseconds.

SPIROCYCLIC ISOXAZOLINES AS ANTIPARASITIC AGENTS

The invention recites spirocyclic isoxazoline derivatives of Formula (1) stereoisomers thereof, veterinary or pharmaceutical acceptable salts thereof, compositions thereof, processes for making, and their use as a parasiticide in an animal. The variables