25017-13-4Relevant articles and documents
SYNTHESIS OF AROMATIC FLUORIDES BY THE REACTION OF FLUOROHALOCARBENES WITH CYCLOPENTADIENE DERIVATIVES UNDER PHASE TRANSFER CATALYSIS CONDITIONS
Volchkov, N. V.,Zabolotskikh, A. V.,Lipkind, M. B.,Nefedov, O. M.
, p. 1782 (1989)
-
Synthesis of pharmacologically relevant indoles with amine side chains via tandem hydroformylation/fischer indole synthesis
Schmidt, Axel M.,Eilbracht, Peter
, p. 5528 - 5535 (2007/10/03)
The sequence of hydroformylation and Fischer indole synthesis starting from amino olefins and aryl hydrazines is described. In a convergent manner, the two units bearing pharmacologically relevant substituents are assembled in the final indolization step. This modular and diversity-oriented approach to tryptamines and homotryptamines can be conducted in water and allows synthesis of branched and nonbranched tryptamines as well as tryptamine-based pharmaceuticals such as the 5-HT1D agonist L 775 606.
Substituted 4-aminocyclohexanol compounds
-
Page 13, (2010/02/09)
4-aminocyclohexanol compounds, processes for their preparation, pharmaceutical formulations comprising these compounds and the use of substituted 4-aminocyclohexanol compounds for the preparation of pharmaceutical formulations and for the treatment of div