250378-69-9

Upstream product

• 250378-78-0 (S)-2-methoxy-1-((7R,9R,10S)-7-methoxy-9,10-dimethyl-8-oxa-1,4-dithiaspiro[4.5]decan-7-yl)-2-oxoethyl benzoate 
• 1336892-19-3 C₁₃H₂₄O₃S₂ 
• 250378-76-8 tert-Butyl syn-(4S,5R)-5-hydroxy-4-methyl-3-oxohexanoate 
• 98-88-4 benzoyl chloride 

Downstream Products

• 175085-04-8 (S)-2-methoxy-1-((2R,5R,6R)-2-methoxy-5,6-dimethyl-4-methylenetetrahydro-2H-pyran-2-yl)-2-oxoethyl benzoate 
• 175085-05-9 (S)-2-(benzoyloxy)-2-((2R,5R,6R)-tetrahydro-2-methoxy-5,6-dimethyl-4-methylene-2H-pyran-2-yl)acetic acid 

Relevant academic research and scientific papers

PEDERIN AND PSYMBERIN AGENTS

Compounds that include a pederin, psymberin or pederin/psymberin chimera scaffold. The pederin scaffold includes a substituent at the C10 and/or C13 position that may include a linker that may be conjugated to a targeting moiety. The psymberin scaffold in

Total synthesis of theopederin D

(Chemical Equation Presented) The transformation is complete! The total synthesis of theopederin D (see structure), a potent cytotoxin, has been achieved through oxidative cleavage of a carbon-carbon bond. Other key transformations include an acid-mediate

Simple and efficient synthesis of (+)-methyl 7-benzoylpederate, a key intermediate toward the mycalamides

(equation presented) A simple and efficient method for the synthesis of (+)-methyl 7-benzoylpederate, the left half of pederin, mycalamides, onnamides, and theopederins, was developed. The key reactions include the Evans asymmetric aldol reaction, a thioa