250386-15-3Relevant articles and documents
Cyclic AMP-dependent inhibition of human neutrophil oxidative activity by substituted 2-propynylcyclohexyl adenosine A2A receptor agonists
Sullivan, Gail W.,Rieger, Jayson M.,Michael Scheld,Macdonald, Timothy L.,Linden, Joel
, p. 1017 - 1026 (2001)
1. Novel 2-propynylcyclohexyl-5′-N-ehtylcarboxamidoadenosines, trans-substituted in the 4-position of the cyclohexyl ring, were evaluated in binding assays to the four subtypes of adenosine receptors (ARs). Two esters, 4-{(3-[6-amino-9-(5-ethylcarbamoyl-3
Synthesis of [1,2-3H]ethylamine hydrochloride and [ 3H]-labeled apadenoson for a human ADME study
Hong, Yang,Bonacorsi Jr., Samuel J.,Tian, Yuan,Gong, Sharon,Zhang, Donglu,Humphreys, W. Griffith,Balasubramanian, Balu,Cheesman, Edward H.,Zhang, Zhiqin,Castner, James F.,Crane, Paul D.
, p. 113 - 117 (2008/09/18)
Tritium-labeled [1,2-3H]ethylamine hydrochloride was prepared through a multiple-step sequence in high radioactive specificity. The labeled amine was isolated in high purity following cartridge filtration and used subsequently in the synthesis