250682-79-2

Usage

Chemical Properties

Brown Oil

Upstream product

• 329788-70-7 ((1R,4R)-4-(((tert-butyldimethylsilyl)oxy)methyl)cyclohexyl)methyl 4-methylbenzenesulfonate 
• 180046-62-2 (±)-trans-[4-({[tert-butyl(dimethyl)silyl]oxy}methyl)cyclohexyl]methanol 
• 3236-48-4 trans-1,4-Cyclohexanedimethanol 

Downstream Products

• 250682-80-5 4-prop-2-ynylcyclohexanecarboxylic acid 
• 250386-15-3 Apadenoson 
• 250682-81-6 methyl 4-prop-2-ynylcyclohexanecarboxylate 
• 287179-85-5 (4-prop-2-ynylcyclohexyl)methyl acetate 

Relevant academic research and scientific papers

2-polycyclic propynyl adenosine analogs having A2A agonist activity

The invention provides compounds having the following general formula (I): wherein X, R1, R2, R7 and Z are as described herein.

Cyclic AMP-dependent inhibition of human neutrophil oxidative activity by substituted 2-propynylcyclohexyl adenosine A2A receptor agonists

1. Novel 2-propynylcyclohexyl-5′-N-ehtylcarboxamidoadenosines, trans-substituted in the 4-position of the cyclohexyl ring, were evaluated in binding assays to the four subtypes of adenosine receptors (ARs). Two esters, 4-{(3-[6-amino-9-(5-ethylcarbamoyl-3

Design, synthesis, and evaluation of novel A2A adenosine receptor agonists

We have been interested in the design, synthesis, and evaluation of novel adenosine A2A agonists. Through the use of comparative molecular field analysis (CoMFA) we have generated a training model that includes 78 structurally diverse A2A