25067-30-5

Basic information

• Product Name: cyacrin
• Synonyms: cyacrin
• CAS NO: 25067-30-5
• Molecular Formula: C6H7NO2
• Molecular Weight: 125.12528
• Mol File: 25067-30-5.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 195.1°Cat760mmHg
• Flash Point: 79.2°C
• Appearance: /
• Density: 1.048g/cm³
• CAS DataBase Reference: cyacrin(CAS DataBase Reference)
• NIST Chemistry Reference: cyacrin(25067-30-5)
• EPA Substance Registry System: cyacrin(25067-30-5)

Safety Data

• Hazardous Substances Data: 25067-30-5(Hazardous Substances Data)

Usage

Uses

In adhesives; in manufacture of plastics, electronics, scientific instruments, jewelry, sports equip; in cable joining, manicuring, dentistry, mortuaries, fingerprint development. Polymer nanoparticles as pharmaceutic aid for controlled release drug delivery.

Upstream product

• 462-95-3 formaldehyde diethyl acetal 
• 105-56-6 ethyl 2-cyanoacetate 
• 1448709-78-1 C₅H₁₂N⁽¹⁺⁾*C₂H₃O₂^(1-) 
• 1346549-53-8 N-methyl-N-(2-aldimino-2-methyl-propyl)-pyrrolidinium bis(trifluoromethylsulfonimide) 
• 13987-61-6 N-methylene-tert-butylamine 
• 33797-51-2 eschenmoser's salt 
• 1022085-81-9 N-methylidene-t-butylamine methanesulfonate 
• 50-00-0 formaldehyd 

Downstream Products

• 74598-47-3 ethyl 2-(benzoylmethylene)-4-imino-1,3-dithian-5-carboxylate 
• 78016-56-5 4-Butoxy-benzoic acid 4-((Z)-2-cyano-2-ethoxycarbonyl-vinyl)-phenyl ester 
• 78016-57-6 4-Pentyloxy-benzoic acid 4-((Z)-2-cyano-2-ethoxycarbonyl-vinyl)-phenyl ester 
• 78016-58-7 4-Hexyloxy-benzoic acid 4-((Z)-2-cyano-2-ethoxycarbonyl-vinyl)-phenyl ester 
• 78016-59-8 4-Nonyloxy-benzoic acid 4-((Z)-2-cyano-2-ethoxycarbonyl-vinyl)-phenyl ester 
• 78811-40-2 2-cyano-3-cyclohexylpropionic acid ethyl ester 
• 78016-60-1 4-Pentanoyloxy-benzoic acid 4-((Z)-2-cyano-2-ethoxycarbonyl-vinyl)-phenyl ester 
• 1253427-77-8 ethyl 1-(2-nitro-3-trifluoromethylphenyl)-5-aminopyrazol-4-carboxylate 
• 1449662-22-9 ethyl 1-cyano-4-((trimethylsilyl)oxy)cyclohex-3-enecarboxylate 
• 1449662-25-2 ethyl 1-cyano-4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-((2-(1,1-dioxidothiomorpholino)ethyl)amino)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-yl)cyclohex-3-enecarboxylate 
• 1312815-02-3 methyl 3-(aminomethyl)-1-benzylpyrrolidine-3-carboxylate 
• 19277-46-4 ethyl 9,10-dihydro-9,10-endoethanoanthracene-11-cyano-11-carboxylate 
• 1449662-24-1 ethyl 1-cyano-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-enecarboxylate 
• 1449662-23-0 ethyl 1-cyano-4-(((trifluoromethyl)sulfonyl)oxy)cyclohex-3-enecarboxylate 

Relevant articles and documents

Preparation method of alpha-cyanoacrylate

The invention relates to a preparation method of alpha-cyanoacrylate. The preparation method mainly includes the following steps that methyl cyanoacetate or ethyl cyanoacetate and formaldehyde are subjected to a condensation reaction to obtain a cyanoacrylate prepolymer; the cyanoacrylate prepolymer is cracked and rectified to obtain a methyl cyanoacrylate monomer or an ethyl cyanoacrylate monomer; and an anionic polymerization inhibitor, a free radical polymerization inhibitor, a catalyst and alcohol are added to the methyl cyanoacrylate monomer or the ethyl cyanoacrylate monomer for an esterexchange reaction, and the alpha-cyanoacrylate is obtained. According to the preparation method of the alpha-cyanoacrylate, the long-chain alpha-cyanoacrylate with the high content can be directly prepared, the depolymerization process under high-temperature and high-vacuum conditions is not required, the cost is lowered, the yield of products is increased, and the purity and stability of the products are improved.

Method for synthesizing cyanoacrylate

The invention discloses a method for synthesizing cyanoacrylate. The method comprises steps as follows: cyanoacetic ester and dialkoxymethane are taken as raw materials and have a condensation reaction under the catalytic action of a catalyst, and a reaction mixture of a cyanoacrylate containing oligomer and byproduct alcohol is obtained; the byproduct alcohol and unreacted dialkoxymethane are separated, a stabilizer is added to the remaining reaction mixture, cracking distillation under the reduced pressure is performed, and a cyanoacrylate crude product is obtained; the crude product is purified, and a finished product, namely, cyanoacrylate is obtained. Solid paraformaldehyde is not used any more, the difficulty of solid feeding is reduced, a dehydration step is not required, a dehydrating agent is not required to be used, defects of a condensation polymerization process using solid paraformaldehyde and using a solvent for continuous dehydration in conventional cyanoacrylate synthesis are avoided, the reaction process is easier to control, the process is simple, the operability is high, the method is economical and reasonable, discharge of three wastes and pollution to the environment are greatly reduced, and the method has good social benefits.

A one-pot two-step microwave-assisted synthesis of N1-substituted 5,6-ring-fused 2-pyridones

A fast, versatile and practical one-pot, two-step microwave-assisted protocol for the direct synthesis of N1-substituted 5,6-ring-fused 2-pyridones has been developed. The present method proved to be effective on a series of commercially available aldehydes, ketones and amines and could be profitably exploited in drug-discovery settings for the rapid identification of biologically relevant hit compounds.