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Ficine, also known as ficin, is a proteolytic enzyme derived from the sap of the fig tree (Ficus carica). It is a type of cysteine protease, which means it breaks down proteins at the peptide bonds involving cysteine amino acids. Ficin is used in various applications, including as a meat tenderizer, a digestive aid, and in the clarification of fruit juices and wines. It is also used in the pharmaceutical industry for the production of certain drugs and in research for its potential role in cancer treatment due to its ability to selectively target and break down cancer cells. Ficin is known for its stability and effectiveness at a wide range of pH levels, which makes it a versatile enzyme in industrial and scientific settings.

2520-36-7

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2520-36-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2520-36-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,5,2 and 0 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 2520-36:
(6*2)+(5*5)+(4*2)+(3*0)+(2*3)+(1*6)=57
57 % 10 = 7
So 2520-36-7 is a valid CAS Registry Number.
InChI:InChI=1/C20H19NO4/c1-21-9-5-8-13(21)18-14(22)10-15(23)19-16(24)11-17(25-20(18)19)12-6-3-2-4-7-12/h2-4,6-7,10-11,13,22-23H,5,8-9H2,1H3

2520-36-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 5,7-dihydroxy-8-(1-methylpyrrolidin-2-yl)-2-phenylchromen-4-one

1.2 Other means of identification

Product number -
Other names 5,7-dihydroxy-8-(1-methyl-pyrrolidin-2-yl)-2-phenyl-chromen-4-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2520-36-7 SDS

2520-36-7Downstream Products

2520-36-7Relevant academic research and scientific papers

Synthesis, biological evaluation, and molecular modeling of natural and unnatural flavonoidal alkaloids, inhibitors of kinases

Nguyen, Thanh Binh,Lozach, Olivier,Surpateanu, Georgiana,Wang, Qian,Retailleau, Pascal,Iorga, Bogdan I.,Meijer, Laurent,Guéritte, Fran?oise

, p. 2811 - 2819 (2012/06/01)

The screening of the ICSN chemical library on various disease-relevant protein kinases led to the identification of natural flavonoidal alkaloids of unknown configuration as potent inhibitors of the CDK1 and CDK5 kinases. We thus developed an efficient and modular synthetic strategy for their preparation and that of analogues in order to determine the absolute configuration of the active natural flavonoidal alkaloids and to provide further insights on the structure-activity relationships in this series. The structural determinants of the interaction between some flavonoidal alkaloids with specific kinases were also evaluated using molecular modeling.

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