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Check Digit Verification of cas no

The CAS Registry Mumber 25220-07-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,2,2 and 0 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 25220-07:
(7*2)+(6*5)+(5*2)+(4*2)+(3*0)+(2*0)+(1*7)=69
69 % 10 = 9
So 25220-07-9 is a valid CAS Registry Number.

InChI:InChI=1/C12H16O2/c13-12(14)6-11-9-2-7-1-8(4-9)5-10(11)3-7/h6-10H,1-5H2,(H,13,14)/b11-6-

25220-07-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name	2-(2-adamantylidene)acetic acid

1.2 Other means of identification

Product number	-
Other names	tricyclo<3.3.1.13,7>decylideneacetic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:25220-07-9 SDS

25220-07-9Upstream product

25220-07-9Downstream Products

25220-07-9Relevant academic research and scientific papers

Synthesis and free radical scavenging activity of some new spiropyranocoumarins

Panteleon, Vassiliki,Kostakis, Ioannis K.,Marakos, Panagiotis,Pouli, Nicole,Andreadou, Ioanna

scheme or table, p. 5781 - 5784 (2009/06/18)

A series of novel spiro-substituted 4-hydroxypyranocoumarins and their corresponding dihydropyrano cis-diols has been synthesized. Among them the spiroadamantylpyranocoumarin and the diols can interact with the stable free radical 1,1-diphenyl-2-picrylhydrazyl and scavenge superoxide anions generated in the xanthine-xanthine oxidase system.

6-(2-Adamantan-2-ylidene-hydroxybenzoxazole)-O-sulfamate: A potent non-steroidal irreversible inhibitor of human steroid sulfatase

Schreiner, Erwin P.,Wolff, Barbara,Winiski, Anthony P.,Billich, Andreas

, p. 4313 - 4316 (2007/10/03)

We report the synthesis and results from the in vitro evaluation of 6-(adamantan-2-ylidene-hydroxybenzoxazole)-O-sulfamate 1 as an irreversible inhibitor of human steroid sulfatase (STS). Highly straightforward, condensation of 2-methyl-6-hydroxybenzoxazole with 2-adamantanone, subsequent elimination of water and sulfamoylation provide the title compound in 45% overall yield from the inexpensive 2,4-dihydroxyacetophenone. 1 was found to be a potent irreversible inhibitor of purified human steroid sulfatase (STS) and specific for this enzyme relative to human arylsulfatases A and B. In cellular assays with human keratinocytes, sebocytes and fibroblasts, 1 blocked STS activity with IC50 values in the range of 0.15-0.8 nM, and in MCF-7 breast cancer cells with IC50=2.3 nM, while it did not bind to estrogen receptors α and β. Thus, 1 is a candidate for further investigation of its potential as a drug to be used in androgen- and estrogen-dependent diseases.

A new procedure for the in situ generation of methylene ketenes

Masters, Andrew P.,Sorensen, Ted S.,Tran, Phu Mahn

, p. 1499 - 1502 (2007/10/02)

The reaction of pentacarbonylmanganate anion 3 and 2-bromopropenoyl chlorides 2 leads to 2,4-alkylidenecyclobutane-1,3-diones 5.The latter are formed from dimerization of the corresponding methylene ketenes 1 so that the reaction of 2 and 3 constitutes a

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