25249-06-3

Upstream product

• 97-30-3 methyl-alpha-D-glucopyranoside 
• 32449-92-6 D-glucurono-6,3-lactone 
• 79466-08-3 (-)-Menthol glucuronide 
• 50-99-7 D-glucose 
• 147-79-5 rochelle salt 
• 119738-57-7 apigenin 7-O-[β-D-glucuronopyranosyl-(1->2)]-O-β-D-glucuronopyranoside 
• 2280-44-6 D-Glucose 
• 53962-19-9 desacyl-jegosaponin 
• 72561-81-0 C₉H₁₆O₉ 
• 1207526-30-4 methyl-3,4,5-trihydroxy-6-(5-hydroxy-6-methoxy-4-oxo-2-phenylchroman-7-yloxy)tetrahydro-2H-pyran-2-carboxylate 
• 553677-72-8 22-O-β-D-glucopyranosyl-(1->3)-α-L-arabinopyranosyl-3-O-α-L-rhamnopyranosyl-(1->2)-β-D-galactopyranosyl-(1->2)-β-D-glucuronopyranosyl-soyasapogenol A 
• 1161733-95-4 21-O-acetyl-22-O-β-D-glucopyranosyl-(1->3)-α-L-arabinopyranosyl-3-O-β-D-glucopyranosyl-(1->2)-β-D-galactopyranosyl-(1->2)-β-D-glucuronopyranosyl-soyasapogenol A 
• 1161733-96-5 22-O-β-D-glucopyranosyl-(1->3)-α-L-arabinopyranosyl-3-O-β-D-xylopyranosyl-(1->2)-β-D-galactopyranosyl-(1->2)-β-D-glucuronopyranosyl-soyasapogenol A 

Downstream Products

• 25019-85-6 Glucuronsaeure-isoniazon 
• 96933-51-6 1-p-toluidino-1-deoxy-β-D-glucopyranuronic acid 
• 92109-67-6 6-salicyloylhydrazono-6-deoxy-L-gulonic acid 
• 99562-94-4 5,6-bis-phenylhydrazono-D-lyxo-5,6-dideoxy-hexonic acid 
• 76742-42-2 sodium D-lyxo-5-hexulosonate 
• 63-29-6 D-glucurono-6,3-lactone 
• 79-14-1 glycolic Acid 
• 64-18-6 formic acid 
• 13425-76-8 D-lyxo-hex-5-ulosonic acid 
• 80-69-3 tartronic acid 
• 5627-26-9 ketogulonic acid 
• 87-69-4 tartaric acid 

Relevant academic research and scientific papers

New steroidal glycosides from the stem bark of Mimusops elengi

Two new steroidal glycosides (1 and 2) have been isolated from the ethanolic extract of the stem bark of Mimusops elengi L. and characterized as stigmasta-5,22-dien-3β-ol-3β-D-glucuropyranosyl-(6'β→1'') -Dglucopyranoside (1) and β-sitosterol-3β-(3''',6'''

Cycloartane-type glycosides from Astragalus amblolepis

Five cycloartane-type triterpene glycosides were isolated from the methanol extract of the roots of Astragalus amblolepis Fischer along with one known saponin, 3-O-β-D-xylopyranosyl-16-O-β-D-glucopyranosyl-3β,6α,16β,24(S),25-pentahydroxy-cycloartane. Stru

Two new glycosides from Carduus acanthoides

Two new glycosides, syringic acid-4-O-β-l-arabinopyranoside (1) and kaempferol-3-O-α-l-rhamnopyranosyl-7-O-β-d-glucuronopyranoside (2), were isolated from whole plants of Carduus acanthoides (Asteraceae), and their structures were elucidated on the basis

Two triterpenoid glycosides from the roots of Camellia oleifera and their cytotoxic activity

Two new triterpenoid saponins, oleiferoside N and oleiferoside O, were isolated from the EtOH extract from the roots of Camellia oleifera C. Abel. Their structures were elucidated as 16α-acetoxy-21β,22α-O-diangeloyloxy-23,28-dihydroxyolean-12-ene 3β-O-β-D-xylopyranosyl-(1 → 3)-α-L-arabinopyranosyl-(1 → 3)-β-D-glucuronopyranoside (1), 16α-acetoxy-21β-O-angeloyloxy-23,28-dihydroxy-22α-O-(2-methylbutanoyloxy)olean-12-ene 3β-O-β-D-xylopyranosyl-(1 → 3)-α-L-arabinopyranosyl-(1 → 3)-β-D-glucuronopyranoside (2), on the basis of spectroscopic analyses (IR, ESI-MS, HR-ESI-MS, 1D and 2D NMR) and acid hydrolysis. Both were characterized to be oleanane-type saponins with sugar moieties linked to C-3 of the aglycone. Cytotoxic activities of two saponins were evaluated against four human tumor cell lines (A549, B16, BEL-7402, and MCF-7) by using the MTT in vitro assay. Compounds 1 and 2 showed moderate cytotoxic activities toward the tested cell lines.

Triterpenoid saponins and C-glycosyl flavones from stem bark of Erythrina abyssinica Lam and their cytotoxic effects

Abstract Six new compounds including two oleanane-type triterpenoid saponins (1, 2) and four C-glycosyl flavones (3-6), along with a known saponin (7), three di-C-glycosyl flavones (8-10) and a glycosyl auronol (11), were isolated from the stem bark of Erythrina abyssinica Lam. The structures of the new compounds, identified as 3-O-[α-l-rhamnopyranosyl-(1 → 2)-β-d-galactopyranosyl-(1 → 2)-β-d-glucuronopyranosyl]-22-O-β-d-glucopyranosyl sophoradiol (1), 3-O-[α-l-rhamnopyranosyl-(1 → 2)-β-d-glucopyranosyl-(1 → 2)-β-d-glucuronopyranosyl]-22-O-β-D-glucopyranosyl sophoradiol (2), 6-C-β-glucopyranosyl-8-C-β-quinovopyranosyl apigenin (3), 6-C-β-quinovopyranosyl-8-C-β-glucopyranosyl apigenin (4), 8-C-[6″-O-α-l-rhamnopyranosyl-(1? → 6″]-β-glucopyranosyl 7,4′-dihydroxyflavone (5) and 8-C-[6″-O-β-d-xylopyranosyl-(1?; → 6″)]-β-glucopyranosyl 7,4′-dihydroxyflavone (6), were determined by comprehensive spectroscopic analysis, including 1D and 2D NMR techniques, mass spectrometry and acid hydrolysis. These new compounds together with the known saponins 7 were evaluated for their cytotoxic activity against MCF-7 (estrogen dependent) and MDA-MB-231 (estrogen independent) cell lines. The new saponin 2 exhibited the highest cytotoxic activity among tested compounds, exerting a selective inhibitory effect against the proliferation of MCF-7 cells, with lower IC50 value (12.90 μM) than that of the positive control, resveratrol (13.91μM). Structure-activity relationship of these compounds is also discussed.

Triterpene saponins with hyaluronidase inhibitory activity from the seeds of Camellia sinensis

The MeOH extract of the seeds of Camellia sinensis (L.) KUNTZE gave twelve new saponins (1-12) along with ten known saponins (13-22). These saponins (1-22) showed stronger hyaluronidase inhibitory activity than the positive control, rosmarinic acid.

Triterpenoid saponins from Gypsophila altissima L.

Two new triterpenoid saponins (1, 2) were isolated from the roots of Gypsophila altissima L. (Caryophyllaceae), together with a known compound (3). The structures of new saponins were established as quillaic acid 3-O- β-D-xylopyranosyl-(1→3)- β-D-glucuronopyranoside (1), and 3-O- β-D-galactopyranosyl-(1→2)-[ β-D-xylopyranosyl-(1→3)]- β-D-glucuronopyranosyl quillaic acid 28-O-(6-O-acetyl)- β-D-glucopyranosyl-(1→3)-[ β-D-xylopyranosyl-(1→4)]- α-L-rhamnopyranosyl-(1→2)- β-D-fucopyranoside (2), on the basis of various spectroscopic analyses (including heteronuclear single quantum correlation (HSQC), heteronuclear multiple bond correlation (HMBC), nuclear Overhauser effect spectroscopy (NOESY), total correlation spectroscopy (TOCSY), and high-resolution electrospray ionization mass spectrometry (HR-ESI-MS)) and chemical degradations.

FOETIDISSIMOSIDE A, A NEW 3,28-BIDESMOSIDIC TRITERPENOID SAPONIN, AND CUCURBITACINS FROM CUCURBITA FOETIDISSIMA

Key Word Index-Cucurbita foetidissima; Cucurbitaceae; 3,28-bidesmosidic triterpene saponin; cucurbitacins; structure analysis.A new 3,28-bidesmosidic triterpenoid saponin, foetidissimoside A, was isolated from the roots of Cucurbita foetidissima and its structure established as echinocystic acid 3-O-β-D-glucuropyranoside 28-O-4α-L-rhamnopyranosyl(12)>-α-L-arabinopyranoside mainly by (1)H NMR, (13)C NMR, GC/MS and FABMS analyses.Cucurbitacin B and E with their glucosides, cucurbitacin D and isocucurbitacin B were identified by HPLC analysis.

Acylated oleanane-type triterpene oligoglycosides from the flower buds of Camellia sinensis var. assamica

Eight new acylated oleanane-type triterpene oligoglycosides, floraassamsaponins I, II, III, IV, V, VI, VII, and VIII, were isolated from the flower buds of Camellia sinensis var. assamica. The chemical structures of new constituents were characterized on

Two new oleanane-type triterpene saponins from the leaves of Schefflera sessiliflora de P. V.

From the leaves of Schefflera sessiliflora De P. V., two new oleanane-type triterpene saponins, named scheffleraside A (1), scheffleraside B (2); together with two known saponins, chikusetsusaponin IVa (3), 3-O-[α-l-rhamnopyranosyl-(1 → 3)]-β-d-glucuronopyranosyl hederagenin (4) were isolated by various chromatography methods. Its chemical structure was elucidated by IR, UV, HR-ESI-MS, NMR 1D and 2D experiments and comparison of their NMR data with previous reported data.