252906-75-5

Usage

Uses

Used in Pharmaceutical Industry:
4-Hydroxy-3-piperidinemethanol is used as an intermediate in the synthesis of various drugs, including antihistamines and antiarrhythmic medications, due to its unique chemical structure that facilitates the creation of complex pharmaceutical compounds.
Used in Agrochemical Industry:
4-Hydroxy-3-piperidinemethanol is also utilized as an intermediate in the production of agrochemicals, contributing to the development of effective substances for agricultural applications.
Used in Asymmetric Catalysis:
4-Hydroxy-3-piperidinemethanol serves as a chiral auxiliary in asymmetric catalysis, playing a crucial role in the synthesis of enantiomerically pure compounds, which are essential in various chemical and pharmaceutical processes.
Used in Research and Development:
It is employed in research for its potential applications in the synthesis of complex molecules and natural products, indicating its versatility and importance in advancing scientific knowledge and innovation in chemical synthesis.

InChI:InChI=1/C6H13NO2/c8-4-5-3-7-2-1-6(5)9/h5-9H,1-4H2

Upstream product

• 886-46-4 (3RS,4RS)-1-benzyl-3-hydroxymethyl-piperidin-4-ol 
• 98977-34-5 1-tert-butyl 3-ethyl 4-oxopiperidine-1,3-dicarboxylate 
• 1454-53-1 ethyl 1-benzyl-4-oxopiperidine-3-carboxylate hydrochloride 
• 41276-30-6 C₉H₁₄O₃NC₆H₅ 

Relevant academic research and scientific papers

HEPATITIS B ANTIVIRAL AGENTS

The present invention includes a method of inhibiting, suppressing or preventing HBV infection in an individual in need thereof, comprising administering to the individual a therapeutically effective amount of at least one compound of the invention.

QUINOLONE ANTIBACTERIAL AGENTS

Compounds of formula (I, II, III, IV, V, and VI) and methods for their preparation are disclosed. Further disclosed are methods of making biologically active compounds of formula (I) as well as pharmaceutically acceptable compositions comprising compounds of formula (I). Compounds of formula (I) as disclosed herein can be used in a variety of applications including use as antibacterial agents.

Stereoelectronic substituent effects in polyhydroxylated piperidines and hexahydropyridazines

From the pKa values of the conjugate acids of a large series of hydroxylated piperidines and hexahydropyridazines, a consistent difference in basicity was found between stereo-isomers having an axial or equatorial hydroxyl (OH) group either β o

Iminosugars: Potential inhibitors of liver glycogen phosphorylase

The first synthesis of the single isomers 3R, 4R, 5R); 3S,4S,5S); 3R,4R,5S) and 3S,4S, 5R) of 5-hydroxymethyl-piperidine-3,4-diol from Arecolin is reported, including the synthesis of a series of N-substituted derivatives of the 3R,4R,5R)-isomer Isofagomi

Aza-C-nucleosides as a new class of nucleosides

The synthesis of a new type of nucleoside analogue, aza-C-nucleosides, has been accomplished by the reaction of a number of hydroxylated piperidine and pyrrolidine derivatives with 5-bromouracil in pyridine. The conversion of the aza sugar (+)-cis-N-benzyl-4-hydroxymethylpiperidin-3-ol ((±)-5a) into (±)-5b with trans-configuration was accomplished in five steps by successive tritylation, mesylation, S(N)2 reaction with sodium acetate, deacetylation by treatment with sodium methoxide to give (±)-9 and finally detritylation with 80% acetic acid to give (±)-5b.