886-46-4

Basic information

• Product Name: 3-Piperidinemethanol, 4-hydroxy-1-(phenylmethyl)-
• CAS NO: 886-46-4
• Molecular Formula: C13H19NO2
• Molecular Weight: 221.299
• Mol File: 886-46-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 3-Piperidinemethanol, 4-hydroxy-1-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Piperidinemethanol, 4-hydroxy-1-(phenylmethyl)-(886-46-4)
• EPA Substance Registry System: 3-Piperidinemethanol, 4-hydroxy-1-(phenylmethyl)-(886-46-4)

Safety Data

• Hazardous Substances Data: 886-46-4(Hazardous Substances Data)

Usage

General Description

3-Piperidinemethanol, 4-hydroxy-1-(phenylmethyl)- is a chemical compound with the molecular formula C12H17NO2. It is commonly used in organic synthesis and pharmaceutical research. The compound is a derivative of piperidine and contains a hydroxy group and a phenylmethyl group. It has been studied for its potential antipsychotic and analgesic properties. Additionally, it has shown antibacterial and antifungal activities, making it a potential candidate for the development of new drugs for the treatment of infectious diseases. The compound is also used as a building block in the synthesis of various pharmaceuticals and biologically active compounds.

Upstream product

• 41276-30-6 C₉H₁₄O₃NC₆H₅ 
• 1454-53-1 ethyl 1-benzyl-4-oxopiperidine-3-carboxylate hydrochloride 
• 57611-47-9 1-benzyl-4-oxo-piperidine-3-carboxylic acid methyl ester 
• 956010-25-6 ethyl 1-benzyl-4-hydroxypiperidine-3-carboxylate 

Downstream Products

• 252906-75-5 3-(Hydroxymethyl)piperidin-4-ol 
• 934536-18-2 1-benzyl-3-(tert-butyl-dimethyl-silanyloxymethyl)-piperidin-4-ol 
• 1360651-90-6 (-)-(1R,3R,6R)-8-benzyl-3-fluoro-2,4-dioxa-8-aza-3-phosphadecalin 3-oxide 
• 1360651-91-7 (+)-(1R,3S,6R)-8-benzyl-3-fluoro-2,4-dioxa-8-aza-3-phosphadecalin 3-oxide 
• 1360651-89-3 (-)-(1S,3R,6S)-8-benzyl-3-fluoro-2,4-dioxa-8-aza-3-phosphadecalin 3-oxide 
• 1360651-88-2 (+)-(1S,3S,6S)-8-benzyl-3-fluoro-2,4-dioxa-8-aza-3-phosphadecalin 3-oxide 
• 1360651-85-9 (-)-(1S,3R,6R)-8-benzyl-3-fluoro-2,4-dioxa-8-aza-3-phosphadecalin 3-oxide 
• 1360651-84-8 (-)-(1S,3S,6R)-8-benzyl-3-fluoro-2,4-dioxa-8-aza-3-phosphadecalin 3-oxide 
• 1360651-86-0 (+)-(1R,3R,6S)-8-benzyl-3-fluoro-2,4-dioxa-8-aza-3-phosphadecalin 3-oxide 
• 1360651-87-1 (+)-(1R,3S,6S)-8-benzyl-3-fluoro-2,4-dioxa-8-aza-3-phosphadecalin 3-oxide 
• 1135150-38-7 6-benzylhexahydro-2,2-dimethyl-4H-1,3-dioxino[5,4-c]pyridine 
• 1135150-39-8 6-benzylhexahydro-2,2-dimethyl-4H-1,3-dioxino[5,4-c]pyridine 
• 1135150-52-5 {(3R,4R)-1-benzyl-4-[(2S)-3,3,3-trifluoro-2-methoxy-1-oxo-2-phenylpropoxy]piperidin-3-yl}methyl (αS)-α-methoxy-α-(trifluoromethyl)-benzeneacetate 
• 1135150-53-6 {(3R,4R)-1-benzyl-4-[(2R)-3,3,3-trifluoro-2-methoxy-1-oxo-2-phenylpropoxy]piperidin-3-yl}methyl (αR)-α-methoxy-α-(trifluoromethyl)-benzeneacetate 

Relevant articles and documents

HEPATITIS B ANTIVIRAL AGENTS

The present invention includes a method of inhibiting, suppressing or preventing HBV infection in an individual in need thereof, comprising administering to the individual a therapeutically effective amount of at least one compound of the invention.

5-Quinoline derivatives having an anti-bacterial activity

The present invention describes novel anti-bacterial compounds of the formula (I). These compounds are, amongst others, of interest as inhibitors of DNA gyrase and topoisomerases, for example of topoisomerase II and IV.

2,4-Dioxa-7-aza-, 2,4-dioxa-8-aza-, and 2,4-dioxa-9-aza-3-phosphadecalins as rigid acetylcholine mimetics: Syntheses and characterization

Phosphorylation of suitable piperidine precursors yielded a series of novel decalin-type O,N,P-heterocycles. The title compounds, P(3)-axially and P(3)-equatorially X-substituted, cis- and trans-configurated 2,4-dioxa-7-aza-, 2,4-dioxa-8-aza-, and 2,4-dioxa-9-aza-3-phosphabicyclo[4.4.0]decane 3-oxides (X = Cl, F, 4-nitrophenoxy, and 2,4-dinitrophenoxy), are configuratively fixed and conformationally constrained P-analogues of acetylcholine and as such represent acetylcholine (7-aza and 9-aza isomers) or γ-homo-acetylcholine mimetics (8-aza isomers). Being irreversible inhibitors of acetylcholinesterase (AChE), the compounds are considered to be suitable probes for the investigation of the stereochemical course of the inhibition reaction by 31P-NMR spectroscopy. Moreover, the design of these mimetics will enable studies of molecular interactions with AChE, in particular, the recognition conformation of acetylcholine.