253142-19-7

Basic information

• Product Name: 3-benzyl-2-methoxy-6-methyl-4-pyrimidinone
• Synonyms: 3-benzyl-2-methoxy-6-methyl-4-pyrimidinone
• CAS NO: 253142-19-7
• Molecular Weight: 230.266
• Mol File: 253142-19-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-benzyl-2-methoxy-6-methyl-4-pyrimidinone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyl-2-methoxy-6-methyl-4-pyrimidinone(253142-19-7)
• EPA Substance Registry System: 3-benzyl-2-methoxy-6-methyl-4-pyrimidinone(253142-19-7)

Safety Data

• Hazardous Substances Data: 253142-19-7(Hazardous Substances Data)

Upstream product

• 55996-28-6 6-methyl-2-methoxy-4(3H)-pyrimidinone 
• 1024-41-5 benzyl tosylate 
• 100-39-0 benzyl bromide 

Downstream Products

• 38507-49-2 3-benzyl-1,6-dimethyl-2,4-pyrimidinedione 
• 25589-18-8 3-benzyl-6-methylpyrimidine-2,4(1H,3H)-dione 

Relevant articles and documents

HSAB driven chemoselectivity in alkylation of uracil derivatives. A high yielding preparation of 3-alkylated and unsymmetrically 1,3-dialkylated uracils

A qualitative hardness scale (N134) has been found for the conjugated bases of 2-methoxy-4(3H)-pyrimidinones 1-3 and applied to high yielding chemoselective N3 methylation, ethylation and benzylation reactions. Removal of the 2-methoxy group followed by a second alkylation affords unsymmetrically 1,3-disubstituted uracils.