25409-21-6

Basic information

• Product Name: Benzenepropanoic acid, b-hydroxy-b-(2-phenylethenyl)-, ethyl ester
• CAS NO: 25409-21-6
• Molecular Formula: C19H20O3
• Molecular Weight: 296.366
• Mol File: 25409-21-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzenepropanoic acid, b-hydroxy-b-(2-phenylethenyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, b-hydroxy-b-(2-phenylethenyl)-, ethyl ester(25409-21-6)
• EPA Substance Registry System: Benzenepropanoic acid, b-hydroxy-b-(2-phenylethenyl)-, ethyl ester(25409-21-6)

Safety Data

• Hazardous Substances Data: 25409-21-6(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 98-86-2 acetophenone 
• 623-48-3 ethyl iodoacetae 
• 614-47-1 1,3-diphenyl-propen-3-one 
• 105-36-2 ethyl bromoacetate 

Downstream Products

• 4941-89-3 1t.3-diphenyl-pentadien-(1.3ξ)-oic acid-(5) 
• 19367-40-9 1t.3-diphenyl-pentadien-(1.3ξ)-oic acid-(5)-ethyl ester 

Relevant articles and documents

Vinylogous organocatalytic triple cascade reaction: Forging six stereocenters in complex spiro-oxindolic cyclohexanes

We report a triple vinylogous cascade reaction, yielding valuable spiro-oxindolic cyclohexane derivatives. The three-component domino process proceeds by way of a catalyzed Michael/1,6-addition/vinylogous aldol sequence affording the products with six stereogenic centers and very high control over the stereochemistry. The chemistry is based on a rare example of asymmetric 1,6-addition to linear 2,4-dienals proceeding with complete δ-site selectivity. Key to the reaction development was a directing group positioned at the β-dienal position, which was essential for achieving highly predictable reaction outcomes. Copyright