25433-36-7

Usage

Uses

Used in Pharmaceutical Industry:
5-Methyl-3-(pyridin-2-yl)-1H-1,2,4-triazole is used as a potential candidate for the development of new drugs due to its unique structure and properties. The presence of the pyridine and triazole moieties in the molecule allows for the exploration of its potential therapeutic applications, such as antimicrobial, antifungal, or antiviral agents.
Used in Agrochemical Industry:
In the agrochemical industry, 5-Methyl-3-(pyridin-2-yl)-1H-1,2,4-triazole is used as a potential candidate for the development of new agrochemicals. Its unique structure and properties make it a promising candidate for the creation of novel pesticides, herbicides, or fungicides, which can help address the challenges faced in agriculture, such as pest resistance and crop protection.
Used in Materials Science:
5-Methyl-3-(pyridin-2-yl)-1H-1,2,4-triazole is also used in materials science for the development of new materials with specific properties. The triazole moiety in the molecule can be utilized to create materials with unique characteristics, such as high thermal stability, flame retardancy, or specific optical properties, which can be applied in various industries, including electronics, aerospace, and automotive.
Used in Organic Chemistry Research:
5-Methyl-3-(pyridin-2-yl)-1H-1,2,4-triazole serves as an interesting target for researchers in the field of organic chemistry. Its unique structure and properties provide opportunities for the exploration of new synthetic routes, reaction mechanisms, and the development of novel chemical transformations. This can lead to the discovery of new compounds with potential applications in various fields.
Used in Chemical Biology Research:
In chemical biology, 5-Methyl-3-(pyridin-2-yl)-1H-1,2,4-triazole is used for the investigation of its interactions with biological systems. Its unique structure allows researchers to study its binding properties, potential biological activities, and its role in modulating biological processes. This can contribute to the understanding of molecular mechanisms and the development of new therapeutic strategies.

Upstream product

• 1005-02-3 picolinamidrazone 
• 64-19-7 acetic acid 
• 108-24-7 acetic anhydride 
• 1005-02-3 2-pyridinecarbohydrazonamide 
• 100-70-9 2-Cyanopyridine 
• 54754-52-8 N-(2'-aminobenzoyl)-2-pyridylamidrazone 
• 83507-08-8 N-(2-Methyl-4-oxo-4H-quinazolin-3-yl)-pyridine-2-carboxamidine 
• 75-36-5 acetyl chloride 
• 1068-57-1 acetic acid hydrazide 
• 25433-37-8 C₈H₁₀N₄O 
• 1005-02-3 pyridine-2-carboxamidrazone 

Downstream Products

• 1357506-45-6 2-(5-methyl-2-phenyl-2H-1,2,4-triazol-3-yl)pyridine 

Relevant academic research and scientific papers

Influence of the nature of the substituent in 3-(2-pyridyl)-1,2,4-triazole for complexation with Pd2+

The structure of four new palladium complexes [Pd(HL 2 )Cl 2 and Pd(L 1-3 ) 2 ] with 3-(2-pyridyl)-5-R-1,2,4-triazoles (R=H, CH3, Ph respectively HL 1, HL 2, HL 3 ) wa

Structure-reactivity relationships in the hydrogenation of carbon dioxide with ruthenium complexes bearing pyridinylazolato ligands

Pyridinylazolato (N-N') ruthenium(II) complexes of the type [(N-N')RuCl(PMe3)3] have been obtained in high yields by treating the corresponding functionalised azolylpyridines with [RuCl 2(PMe3)4] in the presence of a base. 15N NMR spectroscopy was used to elucidate the electronic influence of the substituents attached to the azolyl ring. The findings are in agreement with slight differences in the bond lengths of the ruthenium complexes. Furthermore, the electronic nature of the azolate moiety modulates the catalytic activity of the ruthenium complexes in the hydrogenation of carbon dioxide under supercritical conditions and in the transfer hydrogenation of acetophenone. DFT calculations were performed to shed light on the mechanism of the hydrogenation of carbon dioxide and to clarify the impact of the electronic nature of the pyridinylazolate ligands. Copyright

Luminescence comparison of iridium(III) complexes containing symmetric vs. asymmetric quinolinate ligands

We have focused our research on development of the iridium complexes, especially with respect to blue and red emission for OLED. Previously, we prepared bis-[2,3-bis(4-fluorophenyl)quinoxalinato]iridium(acetylacetonate) [Ir(2,3-dpqx-F2)2/

Cationic iridium dendrimers: Synthesis and photophysical properties

Two dendrimers, D1 and D2, containing the cationic iridium complexes (C1 and C2) as cores and truxene-functionalized chromophores as the branches, have been developed by a convergent synthetic strategy. The cationic complexes employ 3-(pyridin-2-yl)-1H-1,

SMALL MOLECULE MODULATORS OF CELL ADHESION

Compounds, particularly compounds having activity as modulators of cadherin-mediated cell adhesion having the following structure: or a pharmaceutically acceptable salt, stereoisomer or prodrug thereof, wherein R1, R2, R3,

Novel light-emitting electrophosphorescent copolymers based on carbazole with an Ir complex on the backbone

Novel light-emitting phosphorescent polymers based on 3,6-carbazole with an iridium complex on the backbone were synthesized by Suzuki polycondensation of A-A and B-B type monomers. Three difluoro-substituted phenylpyridine iridium complexes with differen

Synthesis, Spectrocopic, and Electrochemical Properties of Bis(2,2'- bipyridyl)-ruthenium Compounds of some Pyridyl-1,2,4-triazoles

A series of bis(2,2-bipyridyl)ruthenium compounds with pyridin-2-yl-1,2,4-triazoles has been prepared and characterised by their 1H and 13C n.m.r. spectra and their electronic and electrochemical properties.The 1H n.m.r. spectra have been used to ascertain the co-ordination mode of the ligands.The ligands bind in a bidentate fashion and they have ?-acceptor properties that are weaker than 2,2'-bipyridyl (bipy).The excited-state properties of the complexes are similar to those of 2+ but important variations in the energies of the absorption and the emission maxima are observed.

A SYNTHESIS OF N-(4'-QUINAZOLON-3'-YL)-2-PYRIDINECARBOXAMIDYNES AND THEIR CONVERSION INTO 1,2,4,TRIAZOLES

Treatment of N-(2'-aminobenzoyl)-2-pyrydilamidrazone (1) with ethoxymethylenemalononitrile (EMNN) and ethyl ethoxymethylenecyanoacetate (EMCA) or ortho esters afforded the corresponding N-(2'-alkyl-4'-quinazolon-3'-yl)-2-pyridinecarboxamides (2).Furthermore, treatment of 2 with ethanolic hydrochloric acid caused the ring transformation to give corresponding 5-alkyl-3-(2'-pyridyl)-1H-1,2,4-triazoles (3).