254447-10-4

Upstream product

• 52784-31-3 3-Phenylcyclobutanone 
• 98-80-6 phenylboronic acid 
• 13866-28-9 2,2-dichloro-3-phenylcyclobutanone 
• 100-42-5 styrene 

Downstream Products

• 495-45-4 dypnone 
• 24892-77-1 1,3,4-triphenylbutan-1-one 
• 1533-20-6 1,3-diphenylbutane-1-one 
• 1432045-42-5 1,3-diphenyl-6-(triisopropylsilyl)hex-5-yn-1-one 
• 14944-26-4 3-phenyl-1-tetralone 
• 42509-29-5 4-chloro-1,3-diphenyl-1-butanone 
• 85936-84-1 benzoyl-4 phenyl-3 butyro nitrile 

Relevant academic research and scientific papers

Manganese-Catalyzed Electrochemical Deconstructive Chlorination of Cycloalkanols via Alkoxy Radicals

A manganese-catalyzed electrochemical deconstructive chlorination of cycloalkanols has been developed. This electrochemical method provides access to alkoxy radicals from alcohols and exhibits a broad substrate scope, with various cyclopropanols and cyclobutanols converted into synthetically useful β- and γ-chlorinated ketones (40 examples). Furthermore, the combination of recirculating flow electrochemistry and continuous inline purification was employed to access products on a gram scale.

Manganese-catalyzed oxidative azidation of cyclobutanols: Regiospecific synthesis of alkyl azides by C-C bond cleavage

A novel, manganese-catalyzed oxidative azidation of cyclobutanols is described. A wide range of primary, secondary, and tertiary alkyl azides were generated in synthetically useful yields and exclusive regioselectivity. Aside from linear alkyl azides, oth

Addition/ring-opening reaction of organoboronic acids to cyclobutanones catalyzed by rhodium(I)/P(t-Bu)3 complex

An addition/ring-opening reaction of aryl- and alkenylboronic acids to cyclobutanones took place in 1,4-dioxane at 100 °C in the presence of a rhodium(I) catalyst bearing tri-t-butylphosphine, affording ring-opened ketones. Mechanistically, the reaction proceeded through the addition of an organorhodium species to the carbonyl group of a cyclobutanone and a subsequent ring-opening of the resulting rhodium cyclobutanolate through β-carbon elimination. A deuterium-labeling experiment revealed that an alkylrhodium species generated by the β-carbon elimination underwent successive β-hydride elimination/re-addition processes to form the η3-oxaallylrhodium intermediate, which was readily protonated to afford the product.