14944-26-4

Basic information

• Product Name: 3-PHENYL-3,4-DIHYDRO-1(2H)-NAPHTHALENONE
• Synonyms: 3-PHENYL-3,4-DIHYDRO-1(2H)-NAPHTHALENONE;3-Phenyl-3,4-dihydronaphthalen-1(2H)-one
• CAS NO: 14944-26-4
• Molecular Formula: C₁₆H₁₄O
• Molecular Weight: 222.28176
• Mol File: 14944-26-4.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-PHENYL-3,4-DIHYDRO-1(2H)-NAPHTHALENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-PHENYL-3,4-DIHYDRO-1(2H)-NAPHTHALENONE(14944-26-4)
• EPA Substance Registry System: 3-PHENYL-3,4-DIHYDRO-1(2H)-NAPHTHALENONE(14944-26-4)

Safety Data

• Hazardous Substances Data: 14944-26-4(Hazardous Substances Data)

Upstream product

• 7664-93-9 sulfuric acid 
• 4374-49-6 3-benzyl-3-phenylpropionic acid 
• 64-19-7 acetic acid 
• 5292-53-5 diethyl benzalmalonate 
• 108-86-1 bromobenzene 
• 118806-74-9 2-carboxy-3,4-diphenylbutyric acid 
• 25315-79-1 ethyl-2-ethylcarboxy-3,4-diphenylbutanoate 
• 6921-34-2 benzylmagnesium chloride 
• 83303-67-7 2-Cyano-3,4-diphenyl-butyric acid ethyl ester 
• 1214-54-6 5-benzylidene Meldrum's acid 
• 848611-12-1 5-(1,2-diphenylethyl)-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 122-57-6 1-Phenylbut-1-en-3-one 
• 66858-76-2 2-Iodo-3-phenyl-1,2,3,4-tetrahydro-naphthalene 
• 621-82-9 Cinnamic acid 

Downstream Products

• 30069-65-9 3-phenylnaphthalen-1-ol 
• 14833-69-3 cis-1-hydroxy-3-phenyltetralin 
• 115902-63-1 3-phenyl-1-tetralone oxime 
• 31367-59-6 3,4-Dihydro-2-methyl-1,3-diphenylnaphthalin 
• 31367-60-9 1,3-diphenyl-2-methylnaphthalene 
• 837-80-9 1-methyl-3-phenylnaphthalene 
• 612-94-2 2-phenylnaphthalene 
• 85049-24-7 3-phenyltetralin-2,2-d₂ 
• 83303-59-7 3-Phenyl-3,4-dihydro-naphthalene-2-carboxylic acid methyl ester 
• 88453-15-0 1,2,2-trideuterio-1-deuteroxy-3-phenyltetralin 
• 115761-64-3 3-phenyl-1-aminonaphthalene 
• 31367-58-5 2-Methyl-3-phenyl-1-tetralon 
• 83303-54-2 1-Oxo-3-phenyl-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid methyl ester 

Relevant articles and documents

Exploring the synthetic potential of a marine transaminase including discrimination at a remote stereocentre

The marine transaminase, P-ω-TA, can be employed for the transamination from 1-aminotetralins and 1-aminoindanes with differentiation of stereochemistry at both the site of reaction and at a remote stereocentre resulting in formation of ketone products with up to 93% ee. While 4-substituents are tolerated on the tetralin core, the presence of 3- or 8-substituents is not tolerated by the transaminase. In general P-ω-TA shows capacity for remote diastereoselectivity, although both the stereoselectivity and efficiency are dependent on the specific substrate structure. Optimum efficiency and selectivity are seen with 4-haloaryl-1-aminotetralins and 3-haloaryl-1-aminoindanes, which may be associated with the marine origin of this enzyme. This journal is

DIRECT B-ARYLATION OF CARBONYL COMPOUNDS

Disclosed is a method for the β-C—H H functionalization of carbonyl compounds that is both selective and broadly applicable. The methods provide direct β-arylation of carbonyl compound with a diverse array of aryl or heteroaryl halides, aryl or heteroryl tosylate, aryl or heteroaryl triflates, or diaryliodonium salts, by palladium catalysis in the presence of a ligand and promoter.