254891-68-4

Basic information

• Product Name: (2S,5S)-5-ethynyl-2-[(p-toluenesulfonyloxy)methyl]tetrahydrofuran
• Synonyms: (2S,5S)-5-ethynyl-2-[(p-toluenesulfonyloxy)methyl]tetrahydrofuran
• CAS NO: 254891-68-4
• Molecular Weight: 280.345
• Mol File: 254891-68-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S,5S)-5-ethynyl-2-[(p-toluenesulfonyloxy)methyl]tetrahydrofuran(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,5S)-5-ethynyl-2-[(p-toluenesulfonyloxy)methyl]tetrahydrofuran(254891-68-4)
• EPA Substance Registry System: (2S,5S)-5-ethynyl-2-[(p-toluenesulfonyloxy)methyl]tetrahydrofuran(254891-68-4)

Safety Data

• Hazardous Substances Data: 254891-68-4(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 254891-67-3 (2S,5S)-5-ethynyl-2-(hydroxymethyl)tetrahydrofuran 
• 254891-74-2 (3S,6R)-3-acetoxy-6-hydroxy-7-(p-tolyenesulfonyloxy)hept-1-yne 
• 254891-72-0 (3S,6R)-3-acetoxy-6,7-(isopropylidenedioxy)hept-1-yne 
• 254891-73-1 (3S,6R)-3-acetoxy-6,7-dihydroxyhept-1-yne 
• 253867-17-3 ethyl (2E,6R)-6,7-(isopropylidenedioxy)hept-2-enoate 
• 254891-69-5 (2S,3S,6R)-2,3-epoxy-6,7-(isopropylidenedioxy)heptan-1-ol 
• 254891-70-8 (2R,3S,6R)-1-chloro-2,3-epoxy-6,7-(isopropylidenedioxy)heptane 
• 254891-71-9 (3S,6R)-3-hydroxy-6,7-(isopropylidenedioxy)hept-1-yne 
• 253867-18-4 (2E,6R)-6,7-(isopropylidenedioxy)hept-2-en-1-ol 
• 173152-84-6 ethyl (R)-3-(2,2-dimethyl-1,3-dioxolan-4-yl)propionate 
• 133008-08-9 (4R)-3-(2,2-dimethyl-1,3-dioxolan-4-yl)propan-1-ol 
• 36326-38-2 ethyl (E)-3-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]acrylate 
• 133008-09-0 (R)-3-(2,2-dimethyl-1,3-dioxolan-4-yl)propanal 

Downstream Products

• 253866-88-5 (2S,5S)-2-ethynyl-5-[(4-fluorophenoxy)methyl]tetrahydrofuran 

Relevant articles and documents

Stereoselective syntheses of pharmaceutically relevant chiral tetrahydrofurans from (S)- and (R)-glyceraldehyde derivatives

A practically simple and flexible method of making chiral tetrahydrofurans of therapeutic relevance is reported from glyceraldehyde derivatives as chiral synthons. One of the stereocentres is derived from glyceraldehyde derivatives, while the other one is introduced by Sharpless asymmetric epoxidation using either (+)- or (-)-DIPT.