25525-85-3

Usage

Uses

Used in Flavor and Fragrance Industry:
(E)-3-(furan-2-yl)prop-2-enamide is used as a flavoring agent for its pleasant odor, enhancing the sensory experience of various food and beverages.
Used in Pharmaceutical Industry:
(E)-3-(furan-2-yl)prop-2-enamide is used as a precursor in the production of pharmaceuticals, contributing to the development of new medications.
Used in Organic Synthesis:
(E)-3-(furan-2-yl)prop-2-enamide is used as a starting material in organic synthesis, facilitating the creation of a range of chemical compounds.
Used in Therapeutic Applications:
(E)-3-(furan-2-yl)prop-2-enamide is studied for its potential therapeutic applications due to its anti-inflammatory properties, aiming to treat various diseases and conditions. However, its use in this context is still under investigation and requires further research to ensure safety and efficacy.

Upstream product

• 98-01-1 furfural 
• 625-77-4 N-acetylacetamide 
• 127-09-3 sodium acetate 
• 943143-92-8 2-(acetyloxy)ethyl (2E)-3-(2-furyl)prop-2-enoate 
• 39511-08-5 (E)-3-(2-furanyl)-2-propenal 

Downstream Products

• 6125-63-9 (E)-3-(2-furyl)acrylonitrile 
• 35904-04-2 β-(5-Nitro-2-furyl)-acrylamid 
• 1220981-41-8 C₁₆H₁₁NO₄ 

Relevant academic research and scientific papers

Selective and facile synthesis of α,β-unsaturated nitriles and amides with N-hydroxyphthalimide as the nitrogen source

The direct conversion of α,β-unsaturated aldehydes to corresponding nitriles promoted by Pd(OAc)2 and phthalic acid which was hydrolyzed from N-hydroxyphthalimide (NHPI) has been disclosed. Additionally, it was found that when water was used as the solvent, α,β-unsaturated amides was obtained as the main products in good to excellent yields. It was first reported that NHPI was utilized as the nitrogen source to synthesize α,β-unsaturated nitriles and amides from aldehydes. Control experiment demonstrated that aldehydes undergo a process of oximation and dehydration to form nitriles and amides.

Oxidation of some alkoxy-cycloheptatriene derivatives: unusual formation of furan and furanoids from cycloheptatrienes

The oxidation of some alkoxy tropone and tropone ketal derivatives with singlet oxygen and m-chloroperbenzoic acid was investigated. In most cases furan and furanoid derivatives were isolated. The structures of the formed products were determined by means of spectral data and the formation mechanism of these unusual products is discussed.