25542-64-7

Basic information

• Product Name: 8-Ketopelargonic acid
• Synonyms: 8-Ketopelargonic acid;8-Oxononanoic acid
• CAS NO: 25542-64-7
• Molecular Formula: C₉H₁₆O₃
• Molecular Weight: 172.22
• Mol File: 25542-64-7.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 8-Ketopelargonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Ketopelargonic acid(25542-64-7)
• EPA Substance Registry System: 8-Ketopelargonic acid(25542-64-7)

Safety Data

• Hazardous Substances Data: 25542-64-7(Hazardous Substances Data)

Usage

Uses

8-Oxononanoic Acid (CAS# 25542-64-7) is used in the preparation of a cancer vaccine comprising a synergistic combination of TLR-?9 agonist and a glycolipid-?peptide conjugate. It can also be used to synthesize 10-hydroxycamptothecine derivative useful in treatment of cancer as well as to synthesize glycolipid peptide conjugates for use as antimalarial vaccines.

Upstream product

• 502-49-8 cycloactanone 
• 10363-27-6 2-methylcyclooctanone 
• 30964-01-3 non-8-ynoic acid 
• 27304-77-4 17-hydroxyoleic acid 
• 19480-04-7 6-oxoheptanal 
• 14273-90-6 methyl 6-bromohexanoate 
• 4224-70-8 6-bromohexanoic acid 
• 87224-34-8 7-[5-(3-Methyl-but-2-enoyl)-4,5-dihydro-isoxazol-3-yl]-heptanoic acid methyl ester 
• 59080-48-7 methyl 8-nitrooctanoate 
• 87224-36-0 methyl-8,11-dioxo-10-hydroxy-13-methyl-12-tetradecenoate 
• 20637-00-7 2-Acetyl-octanedioic acid dimethyl ester 
• 75544-92-2 8-Hydroxy-pelargonsaeure 
• 25542-62-5 6-bromo-hexanoic acid ethyl ester 
• 141-97-9 ethyl acetoacetate 

Downstream Products

• 1291090-29-3 6-[8-(4-dimethylamino-phenyl)-2-methyl-7-oxo-3,7-dihydropyrano[3,2-e]indol-1-yl]-hexanoic acid 4-(2-amino-9H-purin-6-yloxymethyl)-benzylamide 
• 1291090-48-6 2-(8-(4-(dimethylamino)phenyl)-2-methyl-7-oxo-3,7-dihydropyrano[3,2-e]indol-1-yl)hexanoic acid 
• 53623-10-2 3,11-dimethylnonacosan-2-one 
• 35376-00-2 methyl 7-oxoheptanoate 

Relevant articles and documents

Selective C-C Bond Cleavage of Cycloalkanones by NaNO2/HCl

A novel selective fragmentation of cycloalkanones by NaNO2/HCl has been established. The C-C bond cleavage reaction proceeds smoothly under mild conditions, selectively affording versatile keto acids or oxime acids. The methodology can streamline the synthesis of valuable chiral molecules and isocoumarins from readily available feedstocks.

SILYL NITRONATES IN ORGANIC SYNTHESIS. SYNTHESYS OF PROSTAGLANDIN INTERMEDIATES

The target molecule 1b has been prepared by a new methodology via silyl nitronates and 2-isoxazolines.Since 1a was converted earlier into PGE1 our approach constitutes a novel entrance to prostaglandins.

Synthesis of 3,11 dimethyl 2 nonacosanone, a contact courting pheromone of the German cockroach

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