2564-18-3

Upstream product

• 6673-14-9 1,5-bis-(4-dimethylamino-phenyl)-penta-1,4-dien-3-one 
• 100-63-0 phenylhydrazine 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 98303-49-2 (1E,4E)-1,5-bis[4-(N,N-dimethylamino)phenyl]-1,4-pentadien-3-one 
• 59-88-1 phenylhydrazine hydrochloride 

Downstream Products

• 96481-55-9 2-methylpent-1-en-3-ol 
• 71195-14-7 2-methyl-3-penten-2-ol 

Relevant academic research and scientific papers

BLUE LIGHT BLOCKLING SYSTEM CONTAINING PYRAZOLINE OR/AND BENZOIC ACID COMPOUNDS

The present invention relates to an blue light blocking system characterized in that the blue light blocking agents possess the structure of a pyrazoline of the formula (I) or/and a phenylacrylic acid of the formula (II). The compounds of formula (I) or / and formula (II) fully cover the range of short-wavelength blue light to protect eyes; it can also selectively absorb long-wavelength blue light, so that the transmitted light can provide a particularly good visual experience to humans. The invention is applicable to products such as optical films, optical lenses, goggles, skin care, lighting devices, paints, adhesives, or panels. These products have a light-colored appearance and the penetrating light provides an excellent visual experience for humans.

Antibacterials and antimycotics: Part 1: Synthesis and activity of 2- pyrazoline derivatives

A series of 3-styryl-1,5-diphenyl and 5-styryl-1,3-diphenyl 2- pyrazolines of different substitutions has been synthesized by condensation of substituted α,β-unsaturated ketones with phenylhydrazine hydrochloride in presence of catalytic amount of concentrated HCl. Compounds in the 3- styryl series had OMe, NMe2, NO2, OH and isopropyl substituents and those in the 5-styryl series had OMe, NMe2 and NO(s). The 3-styryl-1,5-diphenyl compounds showed little variation in antibacterial activity towards gram- positive and gram-negative bacteria in terms of geometric mean minimum inhibitory concentrations (MIC). The 4',4-NMe2, 4',4-NO2 and 4',4-OMe compounds were found to possess the highest activity in the series. The 5- styryl-1,3-diphenyl series showed lower activities than the 3-styryl series. The in vitro antimycotic activity of the 4',4-OH and 2',2-OH substituted compounds showed good activity than the other molecules in the two series.