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2-chloro-N-(4-hydroxyphenyl)-N-methylacetamide is a chemical compound with the molecular formula C9H10ClNO2. It is an organic compound that belongs to the class of amides, specifically a substituted acetamide. The structure of 2-chloro-N-(4-hydroxyphenyl)-N-methylacetamide features a 2-chloro group attached to the acetamide backbone, a 4-hydroxyphenyl group connected to the nitrogen atom, and a methyl group also attached to the nitrogen. 2-chloro-N-(4-hydroxyphenyl)-N-methylacetamide is known for its potential applications in pharmaceuticals and as a chemical intermediate. It is characterized by its white crystalline appearance and is soluble in various organic solvents. Due to its specific functional groups, it can participate in a range of chemical reactions, making it a versatile building block in organic synthesis.

2567-80-8

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2567-80-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2567-80-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,5,6 and 7 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2567-80:
(6*2)+(5*5)+(4*6)+(3*7)+(2*8)+(1*0)=98
98 % 10 = 8
So 2567-80-8 is a valid CAS Registry Number.

2567-80-8Relevant academic research and scientific papers

A new chemical tool for exploring the physiological function of the PDE2 isozyme

Chambers, Robert J.,Abrams, Kristin,Garceau, Norman Y.,Kamath, Ajith V.,Manley, Christopher M.,Lilley, Susan C.,Otte, Douglas A.,Scott, Dennis O.,Sheils, Alissa L.,Tess, David A.,Vellekoop, A. Samuel,Zhang, Yan,Lam, Kelvin T.

, p. 307 - 310 (2006)

Oxindole (2) is a potent and selective PDE2 inhibitor with a favorable ADME, physiochemical and pharmacokinetic profile to allow for use as a chemical tool in elucidating the physiological role of PDE2.

OXINDOLE DERIVATIVES AND THEIR USE AS PHOSPHODIESTERASE TYPE 2 INHIBITORS

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Page/Page column 13, (2008/06/13)

The present invention provides compounds, methods and kits for treatment of disease states or disorders mediated by PDE2. Oxindole derivatives are provided which have therapeutic use and as PDE2 inhibitors.

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