256935-86-1 Usage
General Description
6-Chloro-1H-indole-5-carboxylic acid is a chemical compound with the molecular formula C9H6ClNO2. It is a derivative of indole and contains a chlorine atom and a carboxylic acid functional group attached to the 5-carbon position of the indole ring. 6-chloro-1H-Indole-5-carboxylic acid is commonly used in the pharmaceutical industry as a building block for the synthesis of various pharmaceutical compounds and intermediates. It is also used as a research chemical in the study of indole derivatives and their potential biological activities. 6-Chloro-1H-indole-5-carboxylic acid is known for its versatility and potential applications in drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 256935-86-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,6,9,3 and 5 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 256935-86:
(8*2)+(7*5)+(6*6)+(5*9)+(4*3)+(3*5)+(2*8)+(1*6)=181
181 % 10 = 1
So 256935-86-1 is a valid CAS Registry Number.
256935-86-1Relevant articles and documents
Utility of Japp-Klingemann reaction for the preparation of 5-carboxy-6-chloroindole via Fischer indole protocol
Chen, Yihui,Shibata, Masayuki,Rajeswaran, Manju,Srikrishnan, Thamarapu,Dugar, Sundeep,Pandey, Ravindra K.
, p. 2353 - 2356 (2007/10/03)
5-Carboxy-6-chloroindole, a precursor for p38 kinase inhibitor, was prepared from 4-amino-2-chloro-3-iodobenzoicacid by following the Japp-Klingemann synthetic approach. The structures of the key intermediates were also confirmed by X-ray analyses. Computational analysis was helpful in understanding the importance of the substituents at the cyclization step of the synthesis.
Preparation of benzimidazole-5-carboxamides and indole-5-carboxamides to treat cardiac failure and other disorders.
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Page column 28, (2008/06/13)
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