257290-68-9

Upstream product

• 120747-84-4 2-aminopyrimidine-5-carboxyaldehyde 
• 126-30-7 2,2-Dimethyl-1,3-propanediol 
• 98-59-9 p-toluenesulfonyl chloride 
• 257290-67-8 5-(5,5-Dimethyl-1,3-dioxan-2-yl)-2-pyrimidinamine 

Downstream Products

• 257290-80-5 2-[5-(5,5-dimethyl-[1,3]dioxan-2-yl)-2-(toluene-4-sulfonylimino)-2H-pyrimidin-1-yl]-acetamide 
• 258276-64-1 HIP-2 
• 258276-66-3 HIP-3 

Relevant academic research and scientific papers

Unusual ring closure reaction of amides with pyrimidines: Novel stereoselective synthesis of hexahydroimidazo[1,2-c]pyrimidines

Hexahydromidazo[1,2-c]pyrimidines 6 were prepared by the reaction of tosylpyrimidines 2 with bromoacetamides 3 in one step. The stereoselectivity of the reaction has been confirmed by X-ray analysis. Imidazo[1,2- a]pyrimidines 5 were obtained on heating h