258276-66-3Relevant articles and documents
Unusual ring closure reaction of amides with pyrimidines: Novel stereoselective synthesis of hexahydroimidazo[1,2-c]pyrimidines
Acero-Alarcoì?n, Alberto,Armero-Alarte, Trinidad,Jorda-Gregori, Joan M.,Rojas-Argudo, Cristina,Zaballos-Garciì?a, Elena,Server-Carrioì?, Juan,Ahjyaje, Fatima Z.,Sepulveda-Arques, Joseì?
, p. 2124 - 2130 (2007/10/03)
Hexahydromidazo[1,2-c]pyrimidines 6 were prepared by the reaction of tosylpyrimidines 2 with bromoacetamides 3 in one step. The stereoselectivity of the reaction has been confirmed by X-ray analysis. Imidazo[1,2- a]pyrimidines 5 were obtained on heating h