25736-86-1

Usage

Uses

Used in Emulsion Polymerization:
POLY(ETHYLENE GLYCOL) (N) MONOMETHACRYLATE is used as a comonomer in emulsion polymerization for its ability to improve the properties of the resulting polymers. It enhances the solubility, flexibility, and compatibility of the polymers, making them suitable for a wide range of applications.
Used in Pharmaceutical Industry:
POLY(ETHYLENE GLYCOL) (N) MONOMETHACRYLATE is used as a thickener, dispersant, and suspending aid in the pharmaceutical industry. Its biocompatibility and non-toxic nature make it an ideal candidate for use in drug formulations, where it can help improve the stability, solubility, and overall performance of the drug.
Used in Cosmetics Industry:
In the cosmetics industry, POLY(ETHYLENE GLYCOL) (N) MONOMETHACRYLATE is used as a thickener, dispersant, and suspending aid for various cosmetic products. Its ability to improve the texture, consistency, and stability of formulations makes it a valuable ingredient in the development of creams, lotions, and other personal care products.
Used in Biomedical Applications:
POLY(ETHYLENE GLYCOL) (N) MONOMETHACRYLATE is also used in biomedical applications, such as in the development of hydrogels and other biomaterials. Its biocompatibility and ability to form stable structures make it a promising material for use in tissue engineering, drug delivery systems, and other medical applications.

InChI:InChI=1/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3

Upstream product

• 75-21-8 oxirane 
• 79-41-4 poly(methacrylic acid) 
• 107-21-1 ethylene glycol 
• 80-62-6 methacrylic acid methyl ester 
• 107-07-3 2-chloro-ethanol 
• 6900-35-2 potassium methacrylate 
• 920-46-7 Methacryloyl chloride 
• 463-49-0 1,2-propanediene 
• 201230-82-2 carbon monoxide 
• 80-55-7 ethyl 2-hydroxy-2,2-dimethylethanoate 
• 594-61-6 2-methyllactic acid 
• 2110-78-3 methyl 2-hydroxy-2-methylpropionate 
• 2421-28-5 dianhydride of benzophenone-3,4,3',4'-tetracarboxy acid 
• 67-56-1 methanol 

Downstream Products

• 19117-13-6 2-Methyl-acrylic acid 2-(heptyl-{4-[1-(4-{heptyl-[2-(2-methyl-acryloyloxy)-ethoxy]-phosphinoyloxy}-phenyl)-1-methyl-ethyl]-phenoxy}-phosphinoyloxy)-ethyl ester 
• 13695-27-7 ethylene glycol monomethacrylate chloroformate 
• 91375-72-3 <(2'-chlorocarbonyloxy)ethyl>-2-methyl-3-chloropropionate 
• 105501-11-9 sodium 2,3-bis(hexadecyloxy)propyl 3-methacryloyl-3-oxapropyl phosphate 
• 132153-56-1 2-methacryloyloxyethyl-D-mannoside 
• 132153-65-2 galactosyloxyethyl methacrylate 
• 29712-66-1 OKM-2 
• 108595-19-3 1-hexa-2t,4t-dienyloxy-2-methacryloyloxy-ethane 
• 213453-08-8 2-(2-bromoisobutyryloxy)ethyl methacrylate 
• 17407-12-4 dimethyl-di(methacroyloxy-1-ethoxy)silane 
• 17650-46-3 2-methylacrylic acid 2-(ethyloxycarbonyloxy)ethyl ester 
• 51293-89-1 2-methylacrylic acid 2-(butylcarbamoyloxy)ethyl ester 
• 41261-99-8 cinnamoyloxyethyl methacrylate 
• 61790-90-7 polysiloxane 

Relevant academic research and scientific papers

Protein-Grafted Polymers Prepared Through a Site-Specific Conjugation by Microbial Transglutaminase for an Immunosorbent Assay

Protein-polymer conjugates have been developed in many fields. Most hybrids are composed of one protein attached to one or several polymer chains. The other form of hybrid involves the construction of multiple proteins on one polymer chain, thereby facili

Efficient synthesis of polymer prodrug by thiol-acrylate michael addition reaction and fabrication of Ph-responsive prodrug nanoparticles

In this study, an efficient method is proposed for the synthesis of polymer prodrug with acid-liable linkage via thiol-acrylate Michael addition reaction of the camptothecin with tethering acrylate group and polymer scaffold containing multiple thiol grou

Tumor nano vaccine Preparation method and application thereof

The invention relates to a tumor nano vaccine and a preparation method and application thereof. The tumor nano vaccine is a composite nano micelle composed of an acid sensitive polymer immunologic adjuvant conjugate and a tumor-related antigen/antigen peptide, and the acid sensitive polymer immunoadjuvant conjugate has the structure shown 1. The tumor nano vaccine can selectively target lymph nodes and efficiently deliver tumor neoantigen and immunologic adjuvant to dendritic cells, activate antigen-specific T-cell immune effect, and efficiently inhibit tumor growth and metastasis.

All-cell tumor nano vaccine Preparation method and application thereof

The invention relates to a whole-cell tumor nano vaccine and a preparation method and application thereof. The whole-cell tumor nano vaccine is a nano-vaccine of an acid-sensitive polymer-loaded immunoadjuvant, a nano-vaccine of an acid-sensitive polymer - immunologic adjuvant conjugate, a nano vaccine coated with an engineering tumor cell membrane, or a combination of the two. To the whole-cell tumor nano vaccine, dendritic cell antigen presenting efficiency can be enhanced, multiple specific cytotoxic T lymphocytes are activated, efficient anti-tumor recurrence and transfer effects are achieved, and meanwhile, personalized treatment of malignant tumors is facilitated.

BIOGUM AND BOTANICAL GUM HYDROGEL BIOINKS FOR THE PHYSIOLOGICAL 3D BIOPRINTING OF TISSUE CONSTRUCTS FOR IN VITRO CULTURE AND TRANSPLANTATION

Bioink compositions comprising a biomaterial (mammalian, plant based, synthetically derived, or microbially derived) such as a hydrogel and a microbial-, fungal-, or plant-produced polysaccharide, with or without cells, for use in the 3D bioprinting of human tissues and scaffolds are described. The bioink compositions have excellent printability and improved cell function, viability and engraftment. Furthermore, the bioink compositions can be supplemented through the additional of auxiliary proteins and other molecules such as growth factors including extracellular matrix components, Laminins, super affinity growth factors and morphogens. The bioink compositions can be used under physiological conditions related to 3D bioprinting parameters which are cytocompatible (e.g. temperature, printing pressure, nozzle size, bioink gelation process). The combination of a biogum-based biomaterial together with mammalian, plant, microbial or synthetically derived hydrogels exhibited improvement in printability, cell function and viability compared to tissues printed with bioink not containing biogums.

Acrylate monomer having hydrophilic end group and a method for preparing the same

More particularly, the present invention relates to an acrylate monomer having a high-purity hydrophilic terminal group which does not contain unreacted 1 water or undesirable by-products, and a method for producing the acrylate monomer. These acrylate monomers are substantially free of polymerization inhibitors. Chemical Formula 1. In Chemical Formula 1, R. 1 Chem. R. 2 Chem. R. 3 May be H, or linear, branched or cyclic C, independently of each other. 1 -C12 alkyl group. R4 Is linear, branched or cyclic C. 1 -C12 alkyl Or C1 -C12 It is alkoxy group, wherein alkyl group carbon atoms can be unsubstituted or substituted with oxygen atoms, n Is an integer selected from 1 and 10.

Runge-Kutta analysis for optimizing the Zn-catalyzed transesterification conditions of MA and MMA with diols to maximize monoesterified products

Terminal hydroxylated acrylates and methacrylates were prepared by catalytic transesterification of acrylates and methacrylates with diols catalyzed by a system of a tetranuclear zinc alkoxide, [Zn(tmhd)(OMe)(MeOH)]4 (1a), with 4 equiv. of 2,2′-bipyridine (L1). The reaction time to reach the equilibrium state was analyzed by kinetic studies and a curve-fitting analysis based on the Runge-Kutta method for optimizing the best reaction conditions for mono-esterification. In addition to these kinetic analyses, DFT calculations estimated a proposed mechanism of the catalytic transesterification. This journal is

Phosphate cross-linking agent and preparation method thereof, phosphate-based cross-linked gel polymer electrolyte and preparation method and application thereof

According to the invention, the safety of the battery can be improved based on introduction of phosphate into the gel polymer electrolyte, , the adjustable flexibility is improved by introduction of aPEO chain segment, and the stability and the polymerization capability are improved by introduction of acrylate; thus, further research is carried out on the basis of the prior art, the polyfunctional phosphate cross-linking agent is obtained and is applied to the preparation of the phosphate-based cross-linked gel polymer electrolyte, so the cross linking agent can be copolymerized with other functional monomers to synthesize gel polymer electrolyte; the gel polymer electrolyte has the advantages of simple and convenient preparation method, high ionic conductivity, high thermal stability andgood electrochemical stability, the assembled sodium ion battery has good cycling stability and high-temperature performance, and the phosphate-based gel polymer electrolyte with high safety is provided for quasi-solid sodium/lithium ion batteries.

Method for producing hydroxyethyl methacrylate through ester exchange method

The invention discloses a method for producing hydroxyethyl methacrylate through an ester exchange method, and belongs to a chemical synthesis method. The method comprises the following steps: using methyl methacrylate and ethylene glycol as raw materials, using p-toluene sulfonic acid as a catalyst, using phenothiazine as a polymerization inhibitor, and performing a reaction under the condition of the temperature of 100-120 DEG C so as to prepare a target product. The method disclosed by the invention is safe and simple; compared with catalysts of hexadecyl trimethyl ammonium hydroxide, potassium cyanide, heavy metallic salt type catalysts and the like, the catalyst used in the method disclosed by the invention, namely the p-toluene sulfonic acid, is lower in price, easier to obtain, easier to store and use, smaller in pollution, and better in cooperation use effect with the polymerization inhibitor, and the method is easy in industrialization application.

Supramolecularly Engineered Amphiphilic Macromolecules: Molecular Interaction Overrules Packing Parameters

We report molecular interaction-driven self-assembly of supramolecularly engineered amphiphilic macromolecules (SEAM) containing a single supramolecular structure-directing unit (SSDU) consisting of an H-bonding group connected to a naphthalene diimide chromophore. Two such SEAMs, P1-50 and P2-50, having the identical chemical structure and hydrophobic/hydrophilic balance, exhibit distinct self-assembled structures (polymersome and cylindrical micelle, respectively) due to a difference in the H-bonding group (hydrazide or amide, respectively) of the single SSDU. When mixed together, P1-50 and P2-50 adopted self-sorted assembly. For either series of polymers, variation in the hydrophobic/hydrophilic balance does not alter the morphology reconfirming that self-assembly is primarily driven by directional molecular interaction which is capable of overruling the existing norms in packing parameter-dependent morphology control in an immiscibility-driven block copolymer assembly.