258283-80-6

Basic information

• Product Name: 6-[2,3,4-trimethoxy-6-(2-oxo-2,5-dihydro-furan-3-ylmethyl)-phenyl]-benzo[1,3]dioxole-5-carbaldehyde
• Synonyms: 6-[2,3,4-trimethoxy-6-(2-oxo-2,5-dihydro-furan-3-ylmethyl)-phenyl]-benzo[1,3]dioxole-5-carbaldehyde
• CAS NO: 258283-80-6
• Molecular Weight: 412.396
• Mol File: 258283-80-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-[2,3,4-trimethoxy-6-(2-oxo-2,5-dihydro-furan-3-ylmethyl)-phenyl]-benzo[1,3]dioxole-5-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 6-[2,3,4-trimethoxy-6-(2-oxo-2,5-dihydro-furan-3-ylmethyl)-phenyl]-benzo[1,3]dioxole-5-carbaldehyde(258283-80-6)
• EPA Substance Registry System: 6-[2,3,4-trimethoxy-6-(2-oxo-2,5-dihydro-furan-3-ylmethyl)-phenyl]-benzo[1,3]dioxole-5-carbaldehyde(258283-80-6)

Safety Data

• Hazardous Substances Data: 258283-80-6(Hazardous Substances Data)

Upstream product

• 258283-81-7 6-(6-hydroxymethyl-2,3,4-trimethoxy-phenyl)-benzo[1,3]dioxole-5-carbaldehyde 
• 94838-88-7 2-formyl-4,5-(methylenedioxy)benzeneboronic acid 
• 64490-45-5 2-iodo-3,4,5-trimethoxybenzyl alcohol 
• 145439-08-3 3-(tributylstannyl)-(5H)-furan-2-one 
• 258283-82-8 6-(6-bromomethyl-2,3,4-trimethoxy-phenyl)-benzo[1,3]dioxole-5-carbaldehyde 

Relevant articles and documents

Total Synthesis of (-)-Steganone Utilizing a Samarium(II) Iodide Promoted 8-Endo Ketyl-Olefin Cyclization

A six-step synthesis of (±)-steganone from commercially available 3,4,5-trimethoxybenzyl alcohol features a samarium(II) iodide promoted 8-endo ketyl-olefin coupling to install, in a single transformation, the 8,5 ring system common to the lignan lactones. The racemic synthesis provided the basis for the construction of (-)-steganone, which exploited a chromium tricarbonyl moiety both to establish and protect the desired absolute stereochemistry through key transformations, including a SmI2-promoted 8-endo radical cyclization and two palladium-catalyzed couplings.