258283-82-8

Basic information

• Product Name: 6-(6-bromomethyl-2,3,4-trimethoxy-phenyl)-benzo[1,3]dioxole-5-carbaldehyde
• Synonyms: 6-(6-bromomethyl-2,3,4-trimethoxy-phenyl)-benzo[1,3]dioxole-5-carbaldehyde
• CAS NO: 258283-82-8
• Molecular Weight: 409.233
• Mol File: 258283-82-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-(6-bromomethyl-2,3,4-trimethoxy-phenyl)-benzo[1,3]dioxole-5-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(6-bromomethyl-2,3,4-trimethoxy-phenyl)-benzo[1,3]dioxole-5-carbaldehyde(258283-82-8)
• EPA Substance Registry System: 6-(6-bromomethyl-2,3,4-trimethoxy-phenyl)-benzo[1,3]dioxole-5-carbaldehyde(258283-82-8)

Safety Data

• Hazardous Substances Data: 258283-82-8(Hazardous Substances Data)

Upstream product

• 18173-64-3 tert-butyldimethylsilanol 
• 75921-68-5 1,2,3-trimethoxy-5-(methoxymethyl)benzene 
• 3840-31-1 (3,4,5-trimethoxyphenyl)methanol 
• 6178-44-5 ethyl 3,4,5-trimethoxybenzoate 
• 258283-81-7 6-(6-hydroxymethyl-2,3,4-trimethoxy-phenyl)-benzo[1,3]dioxole-5-carbaldehyde 
• 94838-88-7 2-formyl-4,5-(methylenedioxy)benzeneboronic acid 
• 64490-45-5 2-iodo-3,4,5-trimethoxybenzyl alcohol 

Downstream Products

• 258283-80-6 6-[2,3,4-trimethoxy-6-(2-oxo-2,5-dihydro-furan-3-ylmethyl)-phenyl]-benzo[1,3]dioxole-5-carbaldehyde 

Relevant articles and documents

A concise atroposelective formal synthesis of (-)-steganone

We describe herein the atroposelective formal synthesis of (-)-steganone, a parent member of Steganotaenia araliacea dibenzocyclooctadiene lignan lactones. Our synthesis features an atropodiastereoselective biaryl Suzuki-Miyaura cross-coupling reaction with de up to 99% using as a chiral auxiliary an enantiopure and efficiently converted β-hydroxy sulfoxide derivative. A highly atroposelective formal synthesis of (-)-steganone is described highlighting the use of an enantiopure sulfoxide as a chiral auxiliary in the Suzuki-Miyaura cross-coupling reaction.