25829-61-2

Usage

Uses

Used in Pharmaceutical Industry:
2-(4-Aminophenyl)benzoic acid is used as an intermediate in the production of pharmaceuticals for its potential therapeutic effects in the treatment of various medical conditions, including arthritis and multiple sclerosis.
Used in Dye Industry:
2-(4-Aminophenyl)benzoic acid is used as a raw material in the production of dyes due to its chemical properties.
Used in Perfume Industry:
2-(4-Aminophenyl)benzoic acid is used as a component in the creation of perfumes, contributing to their unique scents.
Used in Organic Synthesis:
2-(4-Aminophenyl)benzoic acid is used as an intermediate in the synthesis of various organic compounds, facilitating the production of a range of chemical products.
Used in Fluorescent Brightening Agents Industry:
2-(4-Aminophenyl)benzoic acid is used in the manufacturing of fluorescent brightening agents, enhancing the properties of these products.

Upstream product

• 3096-57-9 2-amino-9-fluorenone 
• 101-84-8 diphenylether 
• 947-84-2 2-Biphenylcarboxylic acid 
• 18211-41-1 4'-nitro-[1,1'-biphenyl]-2-carboxylic acid 

Downstream Products

• 16309-59-4 4'-(6-Benzyloxycarbonylamino-hexanoylamino)-biphenyl-2-carboxylic acid 
• 85129-45-9 (2'-methoxycarbonyl-4-biphenylyl)ferrocene 
• 85129-44-8 1,1'-bis(2'-methoxycarbonyl-4-biphenylyl)ferrocene 
• 16309-60-7 4'-[6-(4-Chloro-benzyloxycarbonylamino)-hexanoylamino]-biphenyl-2-carboxylic acid 
• 67526-82-3 4'-hydroxy-1,1'-biphenyl-2-carboxylic acid 

Relevant academic research and scientific papers

Construction of a family of biphenyl combinatorial libraries: Structure- activity studies utilizing libraries of mixtures

A set of biphenyl aminoacid building blocks has been synthesized. These were used to construct partially-peptidic combinatorial libraries as equimolar multi-component samples. Activity of members of this library as vitronectin receptor antagonists is described, together with SAR studies of the most active members. These studies illustrate several important features of combinatorial libraries.

Nonpeptide arginine vasopressin antagonists for both V(1A) and V2 receptors: Synthesis and pharmacological properties of 2-Phenyl-4'- [(2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)carbonyl]benzanilide derivatives

A series of compounds structurally related to 4'-[(2,3,4,5-tetrahydro- 1H-1-benzazepin-1-yl)carbonyl]benzanilide was synthesized and demonstrated to have arginine vasopressin (AVP) antagonist activity for both V(1A) and V2 receptors. The introduction of a phenyl or a 4-substituted phenyl group into the ortho position of the benzoyl moiety resulted in an increase in both binding affinity and antagonistic activity. The 2-(4-methylphenyl) derivative (1g) exhibited high antagonistic activities for both V(1A) (8.6- fold) and V2 (38-fold) receptors and high oral activity (8.6-fold) compared with the 2-methyl lead compound (1a). Detail of the synthesis and the pharmacological properties of this series are presented.