25870-67-1

Usage

InChI:InChI=1/C15H10N2O5/c18-15(12-4-8-14(9-5-12)17(21)22)10-3-11-1-6-13(7-2-11)16(19)20/h1-10H/b10-3+

Upstream product

• 504-29-0 2-aminopyridine 
• 555-16-8 4-nitrobenzaldehdye 
• 100-19-6 (4-nitrophenyl)ethanone 
• 1439-43-6 1-(4-nitro-phenyl)-2-(triphenyl-λ⁵-phosphanylidene)-ethanone 
• 19394-08-2 2-(p-Nitrobenzylidenamino)ethanol 
• 84922-40-7 N-(4-nitrobenzylidene)quinolin-6-amine 
• 15970-41-9 4-(4-bromophenyl)-1,2-diaminoimidazole 
• 53215-15-9 1-(p-Nitrophenyl)-2,3-dibromo-3-(4-nitrophenyl)propanone 
• 15970-40-8 1,2-diamino-4-phenyl[1H]imidazole 
• 61098-06-4 (E)-4-[4-nitrobenzylideneamino]-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one 

Downstream Products

• 1245216-24-3 C₁₇H₁₄N₄O₅ 
• 1245215-94-4 C₂₂H₁₆N₄O₅ 
• 59548-24-2 3,5-bis(4-nitrophenyl)-1H-pyrazole 
• 102183-30-2 1,2,5-tri-(4-nitrophenyl)-1H-pyrazole 
• 313532-27-3 2,3-dihydro-2,4-bis(4-nitrophenyl)-1H-benzo[b][1,5]diazepine 
• 1408314-23-7 4,6-bis(4-nitrophenyl)-6H-1,3-thiazin-2-amine 
• 130090-21-0 C₂₂H₁₄N₄O₄ 

Relevant academic research and scientific papers

Design and synthesis of novel natural clinoptilolite-MnFe2O4 nanocomposites and their catalytic application in the facile and efficient synthesis of chalcone derivatives through Claisen-Schmidt reaction

A series of three novel nanocomposites were prepared by modifying the surface of natural clinoptilolite using various amounts of manganese ferrite (MnFe2O4) nanoparticles. These manganese ferrite-modified nanocomposites (MFO–NC) were fully characterized by XRD, FT-IR, EDX, VSM and TEM analyses. One of these novel nanocomposites with 40?wt% of manganese ferrite in clinoptilolite (MFO–NC-3) showed a strong catalytic behavior in the aldol-type Claisen–Schmidt reaction for the synthesis of chalcones. A strong catalytic synergy was observed between nano-MnFe2O4 particles and natural clinoptilolite in the structure of these nanocomposites. The products with a broad range of substituents on the reactants were efficiently obtained under room-temperature conditions within relatively short reaction times with good to excellent yields in the presence of one of the prepared MFO–NC nanocomposites. This nanocomposite also showed a strong stability and substantial reusability in the synthesis of chalcones.

Transition-Metal-Free N-Arylation of Pyrazoles with Diaryliodonium Salts

A new synthetic method was developed for the N-arylation of pyrazoles using diaryliodonium salts. The transformation does not require any transition-metal catalyst and provides the desired N-arylpyrazoles rapidly under mild reaction condition in the presence of aqueous ammonia solution as a mild base without the use of inert atmosphere. The chemoselectivity of unsymmetric diaryliodonium salts was also explored with large number of examples.

Solvent free oxalic acid catalyzed synthesis of 1,5-benzodiazepines

In the present study 1, 5-benzodiazepines were synthesized from a range of α β-unsaturated ketones and o-phenylendiamine using oxalic acid 10 mol% as a catalyst under solvent free conditions. The yields of the present method are better than the reported method which explains effectiveness of oxalic acid catalyst. The cost effective, resourceful, undemanding and environment friendly are the advantageous aspects of this method.

Design, Synthesis, Antibacterial Activity, and Molecular Docking Studies of Novel Hybrid 1,3-Thiazine-1,3,5-Triazine Derivatives as Potential Bacterial Translation Inhibitor

Some novel hybrid 1,3-thiazine-1,3,5-triazine derivatives were synthesized and tested for antibacterial activity. Compounds 8c and 8f were found active against Gram positive and Gram negative microorganisms. Molecular docking studies have been performed o

Synthesis and antimicrobial activity of some pyrazoline derivatives

The objective of present study is to synthesize and screening of antimicrobial activity of some derivatives of pyrazoline. 1H-[4-nitro phenyl-5-(substituted phenyl)]pyrazoline has been used as a precursor to synthesize some biologically active heterocycles. Reaction of 1-(4-nitrophenyl)-3-(substituted phenyl) prop-2-en-1-one with hydrazine hydrate gave 1H-(3-nitrophenyl-5-(substituted phenyl) pyrazoline which on reaction with benzoyl chloride in pyridine gave 1-benzoyl-(4-nitrophenyl)-5-(substituted phenyl) prazoline and on reaction with acetic acid yields 1-acetyl-(4- nitrophenyl)-5-(substituted phenyl) pyrazoline derivatives. Several derivatives have been synthesized and screened for their antimicrobial efficacy against Bacillus subtilis, Escherichia coli, Staphylococcus aureus and Klebsiella pneumoniae. Antifungal activity against, Aspergillus flavus, Fusarium oxisporum, Aspergillus niger and Trichoderma viridae.

Synthesis of 2-amino-4,5,7-triarylimidazo[1,5-b]pyridazines

The reaction of 4-aryl-1,2-diaminoimidazoles with 1-aryl-2,3-dibromo-3-(4-nitrophenyl)propanones, 2-bromo-1-phenyl-3-(4-chlorophenyl)propenone, and 1,3-diarylpropynones yields 2-amino-4,5,7-triarylimidazo[1,5-b]-pyridazines. The structure of one of these products was determined by x-ray diffraction analysis. 1999 Kluwer Academic/Plenum Publishers.

Electrochemical reduction of certain fluorenyl and xanthenyl olefins

The reduction of certain fluorene and xanthene containing olefins at a mercury electrode using cyclic voltammetry has been investigated.In DMF, fluorene-9-(4-nitrophenyl)methylene (1) reveals two distinct reversible one-electron redox waves corresponding to anion radical and dianion formation.Some other olefins particularly stilbenes (9-14) and substituted propenones (7,8) show commonality in the emergence of at least one distinct reversible reduction couple.Anion radicals of nearly all of the olefins (1-14) studied in this work generated electrochemically or by chemical 1-electron reductants, exhibited considerable stability.

Interactive free energy relationships for non-additive multiple substituent effects in base catalysed condensation of benzaldehydes with acetophenones: A kinetic study

The base-catalysed condensation of benzaldehydes with acetophenones is enhanced by electron-withdrawing substituents in both starting compounds.The magnitude of ρ-value obtained for various substituents in the benzaldehyde moiety decreases with the introduction of electron-withdrawing groups in the para position of acetophenone moiety.

Co-condensation of 2-Aminopyridine, Aromatic Aldehydes, and Ketones

The co-condensation of 2-aminopyridine with aromatic aldehydes and ketones proceeds via the initial formation from the amine and the benzaldehydes of (2-pyridylamino)aryl carbinols, which then react with p-nitroacetophenone to give 3-aryl-1-(4-nitrophenyl

SYNTHESIS OF 1,3-DIARYL-4,7-PHENANTHROLINES

A number of new 1,3-diaryl-4,7-phenanthrolines were synthesized by heterocyclization of arylidene-6-quinolylamines with acetophenones in the presence of an acidic catalyst.Intermediate amino ketones and side products, viz., N-(R1-benzyl)-6-quinolylamines and α,β-unsaturated ketones, were isolated.The IR, UV, PMR, and mass spectra of the synthesized compounds are discussed.