259199-34-3

Basic information

• Product Name: 6-[2-(4-methoxy-phenyl)-vinyl]-naphthalene-2-carbonitrile
• Synonyms: 6-[2-(4-methoxy-phenyl)-vinyl]-naphthalene-2-carbonitrile
• CAS NO: 259199-34-3
• Molecular Weight: 285.345
• Mol File: 259199-34-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-[2-(4-methoxy-phenyl)-vinyl]-naphthalene-2-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 6-[2-(4-methoxy-phenyl)-vinyl]-naphthalene-2-carbonitrile(259199-34-3)
• EPA Substance Registry System: 6-[2-(4-methoxy-phenyl)-vinyl]-naphthalene-2-carbonitrile(259199-34-3)

Safety Data

• Hazardous Substances Data: 259199-34-3(Hazardous Substances Data)

Upstream product

• 56358-62-4 6-formyl-2-naphthonitrile 
• 1530-38-7 ((4-methoxyphenyl)methyl)triphenylphosphonium bromide 
• 1255871-55-6 6-bromonaphthalene-2-carboxamide 
• 637-69-4 4-Methoxystyrene 
• 91065-17-7 6-bromo-naphthalene-2-carbonitrile 
• 5773-80-8 6-bromo-2-naphthoic acid 
• 145369-29-5 trifluoromethanesulfonic acid 6-cyano-naphthalen-2-yl ester 
• 259199-33-2 2-cyano-6-vinylnaphthalene 
• 52927-22-7 6-cyano-2-naphthol 
• 15231-91-1 6-bromo-naphthalen-2-ol 

Downstream Products

• 259199-39-8 tert-butyl 4-[2-(6-cyano-2-naphthyl)ethyl]phenoxyacetate 
• 259199-37-6 (E)-tert-butyl 4-[2-(6-cyano-2-naphthyl)vinyl]phenoxyacetate 

Relevant articles and documents

Novel amidrazone derivatives: Design, synthesis and activity evaluation

A series of new 6-styryl-naphthalene-2-amidrazone derivatives were synthesized and evaluated as potential ASIC1a inhibitors. Among them, compound 5e showed the most activity to inhibit [Ca2+]i. elevation in acid-induced articular chondrocytes. Together with the important role of ASIC1a in the pathogenesis of tissue acidification diseases including rheumatoid arthritis, these results might provide a meaningful hint or inspiration in developing drugs targeting at tissue acidification diseases.