259522-66-2

Basic information

• Product Name: 7,10,13-tri(triethylsilyl)-2-debenzoyl-2-(3-ethenylbenzoyl)-10-deacetylbaccatin III
• Synonyms: 7,10,13-tri(triethylsilyl)-2-debenzoyl-2-(3-ethenylbenzoyl)-10-deacetylbaccatin III
• CAS NO: 259522-66-2
• Molecular Weight: 913.425
• Mol File: 259522-66-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 7,10,13-tri(triethylsilyl)-2-debenzoyl-2-(3-ethenylbenzoyl)-10-deacetylbaccatin III(CAS DataBase Reference)
• NIST Chemistry Reference: 7,10,13-tri(triethylsilyl)-2-debenzoyl-2-(3-ethenylbenzoyl)-10-deacetylbaccatin III(259522-66-2)
• EPA Substance Registry System: 7,10,13-tri(triethylsilyl)-2-debenzoyl-2-(3-ethenylbenzoyl)-10-deacetylbaccatin III(259522-66-2)

Safety Data

• Hazardous Substances Data: 259522-66-2(Hazardous Substances Data)

Upstream product

• 194720-19-9 7,10,13-tris(triethylsilyl)-10-deacetylbaccatin III 
• 994-30-9 triethylsilyl chloride 
• 32981-86-5 10-deacetylbaccatin III 
• 28447-20-3 3-vinylbenzoic acid 
• 204580-30-3 10-O-deacetyl-2-O-debenzoyl-7,10,13-O-tris(triethylsilyl)baccatin III 

Downstream Products

• 259522-74-2 2-debenzoyl-2-(3-vinylbenzoyl)-7-triethylsilyl-10-deacetyl-10-propanoylbaccatin III 
• 618886-85-4 2-debenzoyl-2-(3-ethenylbenzoyl)-3'N-debenzoyl-3'N-(3-iodobenzoyl)-2'-triethylsilyl-7-triethylsilylpaclitaxel 
• 618886-84-3 2-debenzoyl-2-(3-ethenylbenzoyl)-3'N-debenzoyl-3'N-(3-iodobenzoyl)-2'-triisopropylsilyl-3'-dephenyl-3'-(2-methylprop-1-enyl)-7-triethylsilylpaclitaxel 
• 436845-71-5 7-triethylsilyl-2-debenzoyl-2-(3-ethenylbenzoyl)baccatin III 
• 436845-72-6 7-triethylsilyl-2-debenzoyl-2-(3-ethenylbenzoyl)-10-deacetylbaccatin III 
• 618886-99-0 2-debenzoyl-2-(3-ethenylbenzoyl)-10-deacetylbaccatin III 

Relevant articles and documents

Design, synthesis, and biological evaluation of new-generation taxoids

Novel second-generation taxoids with systematic modifications at the C2, C10, and C3′N positions were synthesized and their structure-activity relationships studied. A number of these taxoids exhibited exceptionally high potency against multidrug-resistan

Design, synthesis and biological activity of novel C2-C3′ N-Linked macrocyclic taxoids

A series of novel macrocyclic taxoids was designed and synthesized by connecting the C-2 and C-3′ N positions of the taxoid framework with various tethers. Cytotoxicity of these macrocyclic taxoids was evaluated against a human breast cancer cell line LCC