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259522-74-2

2-debenzoyl-2-(3-vinylbenzoyl)-7-triethylsilyl-10-deacetyl-10-propanoylbaccatin III is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 2-debenzoyl-2-(3-vinylbenzoyl)-7-triethylsilyl-10-deacetyl-10-propanoylbaccatin III

    Cas No: 259522-74-2

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  • 259522-74-2 Structure

  • Basic information

    1. Product Name: 2-debenzoyl-2-(3-vinylbenzoyl)-7-triethylsilyl-10-deacetyl-10-propanoylbaccatin III
    2. Synonyms: 2-debenzoyl-2-(3-vinylbenzoyl)-7-triethylsilyl-10-deacetyl-10-propanoylbaccatin III
    3. CAS NO:259522-74-2
    4. Molecular Formula:
    5. Molecular Weight: 740.964
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 259522-74-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-debenzoyl-2-(3-vinylbenzoyl)-7-triethylsilyl-10-deacetyl-10-propanoylbaccatin III(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-debenzoyl-2-(3-vinylbenzoyl)-7-triethylsilyl-10-deacetyl-10-propanoylbaccatin III(259522-74-2)
    11. EPA Substance Registry System: 2-debenzoyl-2-(3-vinylbenzoyl)-7-triethylsilyl-10-deacetyl-10-propanoylbaccatin III(259522-74-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 259522-74-2(Hazardous Substances Data)

259522-74-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 259522-74-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,9,5,2 and 2 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 259522-74:
(8*2)+(7*5)+(6*9)+(5*5)+(4*2)+(3*2)+(2*7)+(1*4)=162
162 % 10 = 2
So 259522-74-2 is a valid CAS Registry Number.

259522-74-2Downstream Products

259522-74-2Relevant articles and documents

Design, synthesis, and biological evaluation of new-generation taxoids

Ojima, Iwao,Chen, Jin,Sun, Liang,Borella, Christopher P.,Wang, Tao,Miller, Michael L.,Lin, Songnian,Geng, Xudong,Kuznetsova, Larisa,Qu, Chuanxing,Gallager, David,Zhao, Xianrui,Zanardi, Ilaria,Xia, Shujun,Horwitz, Susan B.,Mallen-St. Clair, Jon,Guerriero, Jennifer L.,Bar-Sagi, Dafna,Veith, Jean M.,Pera, Paula,Bernacki, Ralph J.

scheme or table, p. 3203 - 3221 (2009/05/11)

Novel second-generation taxoids with systematic modifications at the C2, C10, and C3′N positions were synthesized and their structure-activity relationships studied. A number of these taxoids exhibited exceptionally high potency against multidrug-resistan

Synthesis and structure-activity relationships of new second-generation taxoids

Ojima, Iwao,Wang, Tao,Miller, Michael L.,Lin, Songnian,Borella, Christopher P.,Geng, Xudong,Pera, Paula,Bernacki, Ralph J.

, p. 3423 - 3428 (2007/10/03)

A series of second-generation taxoids bearing a substituent on the C-2-benzoyl group and modifications at C-3'/C-10 positions was synthesized. These taxoids exhibited 2-3 orders of magnitude higher potency than that of paclitaxel against drug-resistant human breast cancer cell lines. It is also noteworthy that three taxoids showed almost no difference in activity against drug-resistant and drug-sensitive cell lines, which are categorized as 'advanced second generation taxoids'.

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