618886-85-4Relevant articles and documents
Synthesis of novel C2-C3′N-linked macrocyclic taxoids by means of highly regioselective heck macrocyclization
Geng, Xudong,Miller, Michael L.,Lin, Songnian,Ojima, Iwao
, p. 3733 - 3736 (2007/10/03)
(Matrix presented) Novel C2-C3′N-linked macrocyclic taxoids are synthesized using intramolecular Heck reaction in the key step. Macrocyclization proceeds with high regioselectivity in good yield. Taxoids bearing an olefin moiety at C2 and an iodide at C3′