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618886-99-0

2-debenzoyl-2-(3-ethenylbenzoyl)-10-deacetylbaccatin III is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 618886-99-0 Structure

  • Basic information

    1. Product Name: 2-debenzoyl-2-(3-ethenylbenzoyl)-10-deacetylbaccatin III
    2. Synonyms: 2-debenzoyl-2-(3-ethenylbenzoyl)-10-deacetylbaccatin III
    3. CAS NO:618886-99-0
    4. Molecular Formula:
    5. Molecular Weight: 570.637
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 618886-99-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-debenzoyl-2-(3-ethenylbenzoyl)-10-deacetylbaccatin III(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-debenzoyl-2-(3-ethenylbenzoyl)-10-deacetylbaccatin III(618886-99-0)
    11. EPA Substance Registry System: 2-debenzoyl-2-(3-ethenylbenzoyl)-10-deacetylbaccatin III(618886-99-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 618886-99-0(Hazardous Substances Data)

618886-99-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 618886-99-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,1,8,8,8 and 6 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 618886-99:
(8*6)+(7*1)+(6*8)+(5*8)+(4*8)+(3*6)+(2*9)+(1*9)=220
220 % 10 = 0
So 618886-99-0 is a valid CAS Registry Number.

618886-99-0Relevant articles and documents

Design, synthesis and biological activity of novel C2-C3′ N-Linked macrocyclic taxoids

Ojima, Iwao,Geng, Xudong,Lin, Songnian,Pera, Paula,Bernacki, Ralph J.

, p. 349 - 352 (2002)

A series of novel macrocyclic taxoids was designed and synthesized by connecting the C-2 and C-3′ N positions of the taxoid framework with various tethers. Cytotoxicity of these macrocyclic taxoids was evaluated against a human breast cancer cell line LCC

Design, synthesis, and biological evaluation of new-generation taxoids

Ojima, Iwao,Chen, Jin,Sun, Liang,Borella, Christopher P.,Wang, Tao,Miller, Michael L.,Lin, Songnian,Geng, Xudong,Kuznetsova, Larisa,Qu, Chuanxing,Gallager, David,Zhao, Xianrui,Zanardi, Ilaria,Xia, Shujun,Horwitz, Susan B.,Mallen-St. Clair, Jon,Guerriero, Jennifer L.,Bar-Sagi, Dafna,Veith, Jean M.,Pera, Paula,Bernacki, Ralph J.

experimental part, p. 3203 - 3221 (2009/05/11)

Novel second-generation taxoids with systematic modifications at the C2, C10, and C3′N positions were synthesized and their structure-activity relationships studied. A number of these taxoids exhibited exceptionally high potency against multidrug-resistan

Synthesis of novel C2-C3′N-linked macrocyclic taxoids by means of highly regioselective heck macrocyclization

Geng, Xudong,Miller, Michael L.,Lin, Songnian,Ojima, Iwao

, p. 3733 - 3736 (2007/10/03)

(Matrix presented) Novel C2-C3′N-linked macrocyclic taxoids are synthesized using intramolecular Heck reaction in the key step. Macrocyclization proceeds with high regioselectivity in good yield. Taxoids bearing an olefin moiety at C2 and an iodide at C3′

Synthesis and structure-activity relationships of new second-generation taxoids

Ojima, Iwao,Wang, Tao,Miller, Michael L.,Lin, Songnian,Borella, Christopher P.,Geng, Xudong,Pera, Paula,Bernacki, Ralph J.

, p. 3423 - 3428 (2007/10/03)

A series of second-generation taxoids bearing a substituent on the C-2-benzoyl group and modifications at C-3'/C-10 positions was synthesized. These taxoids exhibited 2-3 orders of magnitude higher potency than that of paclitaxel against drug-resistant human breast cancer cell lines. It is also noteworthy that three taxoids showed almost no difference in activity against drug-resistant and drug-sensitive cell lines, which are categorized as 'advanced second generation taxoids'.

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