618886-99-0

Basic information

• Product Name: 2-debenzoyl-2-(3-ethenylbenzoyl)-10-deacetylbaccatin III
• Synonyms: 2-debenzoyl-2-(3-ethenylbenzoyl)-10-deacetylbaccatin III
• CAS NO: 618886-99-0
• Molecular Weight: 570.637
• Mol File: 618886-99-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-debenzoyl-2-(3-ethenylbenzoyl)-10-deacetylbaccatin III(CAS DataBase Reference)
• NIST Chemistry Reference: 2-debenzoyl-2-(3-ethenylbenzoyl)-10-deacetylbaccatin III(618886-99-0)
• EPA Substance Registry System: 2-debenzoyl-2-(3-ethenylbenzoyl)-10-deacetylbaccatin III(618886-99-0)

Safety Data

• Hazardous Substances Data: 618886-99-0(Hazardous Substances Data)

Upstream product

• 194720-19-9 7,10,13-tris(triethylsilyl)-10-deacetylbaccatin III 
• 32981-86-5 10-deacetylbaccatin III 
• 204580-30-3 10-O-deacetyl-2-O-debenzoyl-7,10,13-O-tris(triethylsilyl)baccatin III 
• 28447-20-3 3-vinylbenzoic acid 
• 259522-66-2 7,10,13-tri(triethylsilyl)-2-debenzoyl-2-(3-ethenylbenzoyl)-10-deacetylbaccatin III 

Downstream Products

• 436845-72-6 7-triethylsilyl-2-debenzoyl-2-(3-ethenylbenzoyl)-10-deacetylbaccatin III 
• 259522-74-2 2-debenzoyl-2-(3-vinylbenzoyl)-7-triethylsilyl-10-deacetyl-10-propanoylbaccatin III 
• 618886-85-4 2-debenzoyl-2-(3-ethenylbenzoyl)-3'N-debenzoyl-3'N-(3-iodobenzoyl)-2'-triethylsilyl-7-triethylsilylpaclitaxel 
• 618886-84-3 2-debenzoyl-2-(3-ethenylbenzoyl)-3'N-debenzoyl-3'N-(3-iodobenzoyl)-2'-triisopropylsilyl-3'-dephenyl-3'-(2-methylprop-1-enyl)-7-triethylsilylpaclitaxel 
• 436845-71-5 7-triethylsilyl-2-debenzoyl-2-(3-ethenylbenzoyl)baccatin III 

Relevant articles and documents

Design, synthesis and biological activity of novel C2-C3′ N-Linked macrocyclic taxoids

A series of novel macrocyclic taxoids was designed and synthesized by connecting the C-2 and C-3′ N positions of the taxoid framework with various tethers. Cytotoxicity of these macrocyclic taxoids was evaluated against a human breast cancer cell line LCC

Synthesis of novel C2-C3′N-linked macrocyclic taxoids by means of highly regioselective heck macrocyclization

(Matrix presented) Novel C2-C3′N-linked macrocyclic taxoids are synthesized using intramolecular Heck reaction in the key step. Macrocyclization proceeds with high regioselectivity in good yield. Taxoids bearing an olefin moiety at C2 and an iodide at C3′