2597-26-4

Basic information

• Product Name: 1H-Indole-3-acetic acid, .alpha.-Methyl-
• Synonyms: 1H-Indole-3-acetic acid, .alpha.-Methyl-;2-(1H-indol-3-yl)propanoic acid
• CAS NO: 2597-26-4
• Molecular Formula: C₁₁H₁₁NO₂
• Molecular Weight: 189.21054
• Mol File: 2597-26-4.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Indole-3-acetic acid, .alpha.-Methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-3-acetic acid, .alpha.-Methyl-(2597-26-4)
• EPA Substance Registry System: 1H-Indole-3-acetic acid, .alpha.-Methyl-(2597-26-4)

Safety Data

• Hazardous Substances Data: 2597-26-4(Hazardous Substances Data)

Usage

General Description

1H-Indole-3-acetic acid, alpha-Methyl- is a synthetic chemical compound that belongs to the indole-3-acetic acid (IAA) class of plant hormones. 1H-Indole-3-acetic acid, .alpha.-Methyl- is often used as a plant growth regulator to stimulate root formation and shoot growth in a variety of plants. It acts as a signaling molecule, influencing plant growth and development processes such as cell elongation, organ formation, and fruit development. It is commonly used in agriculture and horticulture to promote root development in cuttings and seedlings, and to increase the yield and quality of fruits and vegetables. Additionally, it has potential applications in biotechnology for the production of transgenic plants with improved growth and stress tolerance traits.

Upstream product

• 120-72-9 indole 
• 78-97-7 2-hydroxy-propionitrile 
• 778-82-5 ethyl 3-indoleacetate 
• 3389-21-7 3-(2-bromoethyl)-1H-indole 
• 124-38-9 carbon dioxide 
• 10006-91-4 ethyl 2-(1H-indol-3-yl)-propionate 
• 338744-37-9 α-methyl-1-methoxycarbonyl-3-indoleacetic acid methyl ester 
• 152906-03-1 α-Methyl-2-carboxy-3-indoleacetic acid 
• 152905-99-2 Diethyl α-methyl-2-(ethoxycarbonyl)-2-indolemalonate 
• 174319-54-1 methyl 3-(2-methoxy-2-oxoethyl)-1H-indole-1-carboxylate 
• 35643-98-2 2-methyl-4-oxo-butyric acid 
• 100-63-0 phenylhydrazine 
• 87-51-4 indole-3-acetic acid 
• 1912-33-0 Indole-3-acetic acid methyl ester 

Downstream Products

• 21299-80-9 (2R)-(3-Indolyl)propionic acid 
• 126979-07-5 4-Methyl-1-phenylpyrano<3,4-b>indol-3-one 
• 126979-08-6 1-<1-(Indol-3-yl)ethyl>-4-methylpyrano<3,4-b>indol-3-one 
• 10006-92-5 (2R)-(-)-2-(3-indolyl)-propan-1-ol 
• 21070-37-1 (S)-(+)-α-methyl-3-indolylacetic acid 
• 141071-79-6 3-(1-Benzylindol-3-yl)propionic Acid 
• 125537-93-1 acremoauxin A 
• 104970-90-3 5,11-dimethyl-1,4-diphenyl-6H-pyridazo<4,5-b>carbazole 
• 94193-98-3 2,3-dibenzoyl-1,4-dimethyl-9H-carbazole 
• 738608-57-6 2-(2-benzoyl-1H-indol-3-yl)-pentan-3-one 
• 338744-39-1 (S)-1-phenylethyl (+)-2-(3-indolyl)propionate 
• 338744-40-4 (R)-1-phenylethyl (-)-2-(3-indolyl)propionate 

Relevant articles and documents

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Site-Selective, Remote sp3 C?H Carboxylation Enabled by the Merger of Photoredox and Nickel Catalysis

A photoinduced carboxylation of alkyl halides with CO2 at remote sp3 C?H sites enabled by the merger of photoredox and Ni catalysis is described. This protocol features a predictable reactivity and site selectivity that can be modulated by the ligand backbone. Preliminary studies reinforce a rationale based on a dynamic displacement of the catalyst throughout the alkyl side chain.

Synthesis of substituted carbazoles and β-carbolines by cyclization of diketoindole derivatives

A new route to substituted β-carbolines and carbazoles is described. Diketoindole intermediates, prepared by Friedel-Crafts acylations of 3-substituted indoles, have been converted to 3-hydroxycarbazoles and β-carbolines in good yields, 51-96% and 82-97%, respectively. This method also allows for the formation of 4-substituted β-carbolines. The application of this methodology to the synthesis of the natural products hyellazole and 6-chlorohyellazole is also described.