260254-80-6

Basic information

• Product Name: (2S,5R)-1-BENZYL-2,5-DIMETHYLPIPERAZINE
• Synonyms: trans-2R,5S-dimethyl-4-benzyl-piperazine;(2S,5R)-1-BENZYL-2,5-DIMETHYLPIPERAZINE 2HCL;(2S,5R)-Benzyl 2,5-Dimethylpiperazine-1-
• CAS NO: 260254-80-6
• Molecular Formula: C₁₃H₂₀N₂
• Molecular Weight: 204.31
• Mol File: 260254-80-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 291.5±20.0 °C(Predicted)
• Appearance: /
• Density: 0.964±0.06 g/cm3(Predicted)
• PKA: 9.35±0.60(Predicted)
• CAS DataBase Reference: (2S,5R)-1-BENZYL-2,5-DIMETHYLPIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,5R)-1-BENZYL-2,5-DIMETHYLPIPERAZINE(260254-80-6)
• EPA Substance Registry System: (2S,5R)-1-BENZYL-2,5-DIMETHYLPIPERAZINE(260254-80-6)

Safety Data

• Hazardous Substances Data: 260254-80-6(Hazardous Substances Data)

Usage

General Description

(2S,5R)-1-Benzyl-2,5-dimethylpiperazine is a chemical compound with a molecular formula C14H22N2. It is a piperazine derivative with a benzyl group attached to the nitrogen atom at position 1 and methyl groups attached to the nitrogen atom at position 2 and 5. (2S,5R)-1-BENZYL-2,5-DIMETHYLPIPERAZINE has potential pharmaceutical applications due to its structural similarity to other piperazine-based drugs. It can be used as a building block for the synthesis of various biologically active compounds, particularly in the development of new drugs targeting neurological disorders and mental health conditions. Additionally, it may also have potential applications in the field of organic synthesis and medicinal chemistry.

InChI:InChI=1/C13H20N2.2ClH/c1-11-9-15(12(2)8-14-11)10-13-6-4-3-5-7-13;;/h3-7,11-12,14H,8-10H2,1-2H3;2*1H/t11-,12+;;/m1../s1

Upstream product

• 3744-87-4 Boc-(R)-Ala 
• 31022-10-3 N-benzyl-L-alanine methyl ester 
• 75-36-5 acetyl chloride 
• 200731-31-3 HATU 
• 159999-80-1 N-benzyl-N-Boc-L-alanine 
• 1072102-00-1 C₁₄H₂₀N₂O₃*ClH 
• 1072101-99-5 C₁₉H₂₈N₂O₅ 
• 1072102-01-2 (3S,6R)-4-benzyl-3,6-dimethylpiperazine-2,5-dione 
• 3138-88-3 C₁₃H₂₀N₂ 
• 100-39-0 benzyl bromide 
• 2815-34-1 2,5-dimethyl-piperazine 
• 431062-00-9 4-benzyl-2R,5S-dimethyl-piperazine-1-carboxylic acid tert-butyl ester 
• 3138-88-3 (+/-)-trans-2,5-dimethyl-4-benzyl-piperazine 

Downstream Products

• 1046788-31-1 4-(((2R,5S)-4-benzyl-2,5-dimethylpiperazin-1-yl)methyl)tetrahydro-2H-pyran-4-ol 
• 1046788-13-9 (2S,5R)-1-benzyl-2,5-dimethyl-4-(3,3,3-trifluoropropyl)piperazine 
• 1046787-98-7 (2S,5R)-1-benzyl-2,5-dimethyl-4-(tetrahydro-2H-pyran-4-ylmethyl)piperazine 
• 1046788-54-8 (2S,5R)-1-benzyl-2,5-dimethyl-4-(tetrahydro-2H-pyran-4-yl)piperazine 
• 1046788-05-9 (2S,5R)-1-benzyl-4-(3-methoxypropyl)-2,5-dimethylpiperazine 

Relevant articles and documents

3-AMIDO-PYRROLO[3,4-C]PYRAZOLE-5(1H, 4H,6H) CARBALDEHYDE DERIVATIVES AS INHIBITORS OF PROTEIN KINASE C

The present invention relates to compounds and pharmaceutically acceptable salts of Formula (I): wherein X, R1, R2, R3, R4, R5, R6, R7, and R8 are as defined above. The invention further relates to pharmaceutical compositions comprising the compounds and pharmaceutically acceptable salts and to methods of treating diabetes mellitus and its complications (including in particular diabetic retinopathy, nephropathy or neuropathy), cancer, ischemia, inflammation, central nervous system disorders, cardiovascular disease, Alzheimer's disease and dermatological disease pression, viral diseases, inflammatory disorders, or diseases in which the liver is a target organ

Indole-type derivatives as inhibitors of p38 kinase

The invention is directed to methods to inhibit p38-α kinase using compounds comprising a phenyl or thienyl coupled through a piperidine or piperazine nucleus to an indole residue wherein the indole residue mandatorily has a substituent on the ring nitrogen which is an amino or substituted amino group.

BENZOFURYLPIPERAZINES AND BENZOFURYLHOMOPIPERAZINES: SEROTONIN AGONISTS

The present invention provides serotonergic benzofurylpiperazines of Formula I: where: A is a piperazine of formula: and R, R1, R2, R3, R4, R5, R5', R6, R6', R7, R7', R8, and R8' are as described in the specification.