2815-34-1

Basic information

• Product Name: trans-2,5-Dimethylpiperazine
• Synonyms: 3-enoyl-CoA reductase-like;ANTI-SRD5A2L2 (C-TERM) antibody produced in rabbit;SRD5A2L2;TECRL;MONOCLONAL ANTI-SRD5A2L2 (C-TERMINAL) antibody produced in mouse;Steroid 5-alpha-reductase 2-like 2 protein;Trans-2,3-enoyl-CoA reductase-like;trans-2,5-Dimethylpiperazine 98%
• CAS NO: 2815-34-1
• Molecular Formula: C₆H₁₄N₂
• Molecular Weight: 114.19
• EINECS: 203-409-4
• Product Categories: Nitrogen cyclic compounds;Building Blocks;Heterocyclic Building Blocks;Piperazines
• Mol File: 2815-34-1.mol
• Article Data: 6

Chemical Properties

• Melting Point: 115-118 °C(lit.)
• Boiling Point: 162-165 °C(lit.)
• Flash Point: 137 °F
• Appearance: white to dark yellow crystalline powder or crystals
• Density: 0.53
• Vapor Pressure: 1.83mmHg at 25°C
• Refractive Index: 1.4628 (estimate)
• Storage Temp.: Flammables area
• Solubility: 50 g/100 mL (20°C)
• PKA: 9.66(at 25℃)
• Water Solubility: 50 g/100 mL (20 ºC)
• BRN: 79886
• CAS DataBase Reference: trans-2,5-Dimethylpiperazine(CAS DataBase Reference)
• NIST Chemistry Reference: trans-2,5-Dimethylpiperazine(2815-34-1)
• EPA Substance Registry System: trans-2,5-Dimethylpiperazine(2815-34-1)

Safety Data

• Hazard Codes: F,Xn,C
• Statements: 11-21-35-20/21/22-22-2017/11/21
• Safety Statements: 16-27-36/37/39-7/9-45-33-26-36-7/8
• RIDADR: UN 2926 4.1/PG 2
• WGK Germany: 3
• RTECS: TL5950000
• HazardClass: 4.1
• PackingGroup: III
• Hazardous Substances Data: 2815-34-1(Hazardous Substances Data)

Usage

Chemical Properties

white to dark yellow crystalline powder

Uses

trans-2,5-Dimethylpiperazine is a C-alkyl substituted piperazine used in the preparation of opioid receptor ligands as well as other biologically active compounds.

InChI:InChI=1/C6H14N2/c1-5-3-8-6(2)4-7-5/h5-8H,3-4H2,1-2H3/p+2/t5-,6-/m0/s1

Upstream product

• 123-32-0 2,5-dimethyl-pyrazine 
• 6168-72-5 2-Amino-1-propanol 
• 78-96-6 3-amino-2-propanol 
• 5856-63-3 (2R)-2-aminobutan-1-ol 
• 64-17-5 ethanol 
• 64-19-7 acetic acid 
• 306-44-5 propanone 1-oxime 
• 106-55-8 2,5-dimethylpiperazine 
• 57-55-6 propylene glycol 
• 78-90-0 1,2-diaminopropan 
• 115893-42-0 (β-hydroxy-isopropyl)-(2-hydroxy-propyl)-amine 
• 2294-46-4 bis(2-hydroxy-1-methylethyl)amine 
• 110-97-4 diisopropanolamine 
• 5625-46-7 cyclo(-DL-Ala-DL-Ala-) 

Downstream Products

• 103643-64-7 (+/-)-1-{3-[4-(4-methoxy-3-methyl-benzyl)-phenyl]-propyl}-2r,5t-dimethyl-piperazine 
• 102233-13-6 2r,5t-dimethyl-1-[3-(4-phenoxymethyl-phenyl)-propyl]-piperazine 
• 6286-18-6 2r,5t-dimethyl-piperazine-1,4-dicarboxylic acid diethyl ester 
• 24779-44-0 ethyl trans-2,5-dimethyl-1-piperazinecarboxylate 
• 101788-92-5 1,4-bis-(2,4-dinitro-phenyl)-2r,5t-dimethyl-piperazine 
• 142770-23-8 1,4-bis-(4-chloro-benzoyl)-2r,5t-dimethyl-piperazine 
• 110148-95-3 2,5-dimethyl-1,4-bis-(toluene-4-sulfonyl)-piperazine 
• 102008-16-2 (+/-)-1-benzhydryl-2r,5t-dimethyl-piperazine 
• 112689-38-0 2r,5t-dimethyl-1,4-bis-[(1-nitro-cyclohexyl)-methyl]-piperazine 
• 697728-90-8 (+/-)-1,2r,4,5t-tetramethyl-piperazine 
• 4159-09-5 1,4-dichloro-trans-2,5-dimethylpiperazine 

Relevant articles and documents

Reversible Interconversion between 2,5-Dimethylpyrazine and 2,5-Dimethylpiperazine by Iridium-Catalyzed Hydrogenation/Dehydrogenation for Efficient Hydrogen Storage

A new hydrogen storage system based on the hydrogenation and dehydrogenation of nitrogen heterocyclic compounds, employing a single iridium catalyst, has been developed. Efficient hydrogen storage using relatively small amounts of solvent compared with previous systems was achieved by this new system. Reversible transformations between 2,5-dimethylpyrazine and 2,5-dimethylpiperazine, accompanied by the uptake and release of three equivalents of hydrogen, could be repeated almost quantitatively at least four times without any loss of efficiency. Furthermore, hydrogen storage under solvent-free conditions was also accomplished.

Electromagnetic actuator

An electromagnetic actuator comprising a fixed magnetic pole (11) applied with an electromagnetic coil (14), and a movable magnetic pole (20) provided in the insertion hole (12) of the fixed magnetic pole movably in the axial direction. The movable magnetic pole is provided with a projecting portion (22) tapered along its moving direction, a recessed taper portion (13) corresponding to the projecting taper portion of the movable magnetic pole is formed at the insertion hole of the fixed magnetic pole, and a tubular auxiliary magnetic pole (40) extending in the axial direction from the opening end of the recessed taper portion is provided continuously to the fixed magnetic pole.

Process for preparing Cis-2,6-dimethylpiperazine

This invention relates to a process for the selective preparation of cis-2,6-dimethylpiperazine by reacting (i) a diisopropanolamine mixture comprising compounds having the formulas HN(CH2CH(OH)CH3)2, HN(CH(CH3)CH2OH)2, and HN(CH(CH3)CH2OH)(CH2CH(OH)CH3) or (ii) 1,2-diaminopropane with ammonia and hydrogen in the presence of a hydrogenation catalyst.